Becker Nevus Syndrome

A sporadic syndrome characterized by the presence of a Becker nevus (a late-onset, large, brown birthmark occurring mostly in males that typically develops during childhood or adolescence on the shoulders or upper trunk) in association with unilateral hypoplasia of breast or other cutaneous, muscular, or skeletal defects, all of which usually involve the same side of the body as the nevus. OMIM: 604919

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Nevus (Nevi)
2.	Poland Syndrome
3.	Musculoskeletal Abnormalities
4.	Hypertrichosis
5.	Hamartoma

Experts

1.	Chang, Li-Wei: 1 article (04/2022)
2.	Gehris, Robin: 1 article (04/2022)
3.	Georgesen, Corey: 1 article (04/2022)
4.	Ho, Jonhan: 1 article (04/2022)
5.	Jedrych, Jaroslaw: 1 article (04/2022)
6.	Karunamurthy, Arivarasan: 1 article (04/2022)
7.	Kazlouskaya, Viktoryia: 1 article (04/2022)
8.	Matsumoto, Martha: 1 article (04/2022)
9.	Picarsic, Jennifer: 1 article (04/2022)
10.	Woerner, Audrey: 1 article (04/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Becker Nevus Syndrome:

1.	Actins (F Actin)IBA 10/01/2021 - "Is there a genomic link and common pathogenesis (postzygotic mutations in beta-actin) for Poland syndrome and Becker nevus syndrome?" 01/01/2019 - "In closing, we would like to raise an easy-to-remember 6B's mnemonic, which stands for Becker, Breast, Bone, Bowen's disease, Basal cell carcinoma, and Beta-actin, for the cases of Becker nevus syndrome."
2.	6-bromo-2-naphthyl sulfate (BNS)IBA 11/01/2014 - "Becker nevus syndrome (BNS) is a rare epidermal nevus syndrome characterized with Becker nevus and ipsilateral breast gland hypoplasia or other skin, skeletal and/or muscle tissue disorders. " 04/01/2022 - "Becker nevus (BN) is a benign cutaneous smooth muscle hamartoma that presents with a hyperpigmented patch or plaque with or without hypertrichosis.1 BN may be associated with ipsilateral breast hypoplasia or other musculoskeletal abnormalities, an association which has been termed Becker nevus syndrome (BNS)."
3.	Spironolactone (Aldactone)FDA LinkGeneric 04/01/2022 - "Improvement of Unilateral Breast Hypoplasia With Oral Spironolactone in a Patient With Becker Nevus Syndrome."