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Pick Complex

mutation in MAPT

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease)
2.	Frontotemporal Dementia (Semantic Dementia)
3.	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
4.	Neurodegenerative Diseases (Neurodegenerative Disease)
5.	Multiple System Atrophy

Experts

1.	Kertesz, Andrew: 2 articles (01/2009 - 01/2003)
2.	Gude Sampedro, F: 1 article (06/2019)
3.	Robles Bayón, A: 1 article (06/2019)
4.	Robles, Alfredo: 1 article (07/2009)
5.	Abe, Kazuo: 1 article (03/2006)
6.	Hattori, Noriaki: 1 article (03/2006)
7.	Mihara, Masahito: 1 article (03/2006)
8.	Sakoda, Saburo: 1 article (03/2006)
9.	Sawada, Tohru: 1 article (03/2006)
10.	Munoz, David G: 1 article (01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pick Complex:

1.	SynucleinsIBA 01/15/2003 - "All were variants of frontotemporal degeneration (Pick complex): Pick body dementia, n=3, corticobasals degeneration (CBD), n=4, and tau and synuclein negative ubiquitinated inclusions of the motor neuron disease type, n=3. All shared superficial cortical spongiosis, neuronal loss, and gliosis. " 01/01/2009 - "The underlying histology in FTD/Pick complex is ubiquitin positive tau and synuclein negative neuronal inclusions (FTLD-U) in more than half of autopsies and tau positive CBD/PSP/ Pick bodies (FTLD-T) in the rest. "
2.	UbiquitinIBA 01/01/2009 - "The ubiquitin-tau pathological dichotomy is best considered under the Pick complex umbrella to allow for the significant overlap. " 01/01/2009 - "The underlying histology in FTD/Pick complex is ubiquitin positive tau and synuclein negative neuronal inclusions (FTLD-U) in more than half of autopsies and tau positive CBD/PSP/ Pick bodies (FTLD-T) in the rest. " 11/01/1999 - "The diverse entities that constitute the Pick complex can be identified by applying immunostains for tau and ubiquitin in addition to the Gallyas silver stain."
3.	Protons (Proton)IBA 09/01/2002 - "Proton chemical shift imaging in pick complex." 03/20/2006 - "Disease-specific metabolic changes in Alzheimer's disease and frontotemporal dementia/Pick complex were examined by proton magnetic resonance spectroscopy at 3.0 T. "
4.	polyglutamineIBA 07/01/2009 - "Besides the known Pick complex, there are sufficient data to propose the recognition of the Lewy complex, Alzheimer complex, multisystemic atrophy complex, and polyglutamine complex. " 06/01/2019 - "Neurodegenerative diseases were classified in 4 groups: Alzheimer disease, synucleinopathies, Pick complex, and polyglutamine complex. "
5.	SilverIBA 11/01/1999 - "The diverse entities that constitute the Pick complex can be identified by applying immunostains for tau and ubiquitin in addition to the Gallyas silver stain."
6.	Phospholipids (Phosphatides)FDA LinkGeneric 01/01/1975 - "Due to a strong evidence that this group of diseases represents a new type of phospholipid storage disease the name "Phospholipidosis Type II" (Baar-Wiedemann) or "Phosphoglyceridosis" is proposed, whereas "Phospholipidosis Type I" or "Sphingomyelinosis" should be reserved for the classical Niemann-Pick complex."
7.	Coloring Agents (Dyes)IBA 11/01/1999 - "The diverse entities that constitute the Pick complex can be identified by applying immunostains for tau and ubiquitin in addition to the Gallyas silver stain."
8.	N-acetylaspartate (N-acetyl aspartate)IBA 03/20/2006 - "N-acetylaspartate/creatine+phosphocreatine ratio was reduced in the posterior cingulate cortex in the Alzheimer's disease and frontotemporal dementia/Pick complex patients. "

Therapies and Procedures

1.	Bone Marrow Transplantation (Transplantation, Bone Marrow) 02/01/1990 - "We insist on two aspects: 1) greater importance of enzymatic diagnose for the "Niemann-Pick complex", in view of the overlapping of clinical symptoms, 2) bone-marrow transplantation as therapeutic alternative and its indications."
2.	Acupuncture Therapy 09/15/2023 - "Pick Complex Therapy (PCT) is an innovative and developed theory of collateral acupuncture therapy for HAS. "
3.	Therapeutics 09/15/2023 - "Pick Complex Therapy (PCT) is an innovative and developed theory of collateral acupuncture therapy for HAS. "