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1- (hydroxymethyl)- 3- (3- octylphenyl)cyclobutane

an S1P1/3 receptor antagonist prodrug; structure in first source

Also Known As:

VPC 03090; VPC-03090; VPC03090

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        1-(hydroxymethyl)-3-(3-octylphenyl)cyclobutane: 1
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclobutanes
        1-(hydroxymethyl)-3-(3-octylphenyl)cyclobutane: 1

Experts

1.	David, Marion: 1 article (09/2011)
2.	Huang, Tao: 1 article (09/2011)
3.	Kennedy, Perry C: 1 article (09/2011)
4.	Lynch, Kevin R: 1 article (09/2011)
5.	Macdonald, Timothy L: 1 article (09/2011)
6.	Mathews, Thomas P: 1 article (09/2011)
7.	Peyruchaud, Olivier: 1 article (09/2011)
8.	Tomsig, Jose L: 1 article (09/2011)
9.	Zhu, Ran: 1 article (09/2011)

Related Diseases

1.	Carcinogenesis 09/01/2011 - "Because aberrant S1P signaling has been implicated in carcinogenesis, we applied VPC03090 in an immunocompetent mouse mammary cancer model to assess its antineoplastic potential. "
2.	Neoplasms (Cancer) 09/01/2011 - "Treatment with VPC03090 significantly inhibited the growth of 4T1 primary tumors in mice. "
3.	Breast Neoplasms (Breast Cancer) 09/01/2011 - "Because aberrant S1P signaling has been implicated in carcinogenesis, we applied VPC03090 in an immunocompetent mouse mammary cancer model to assess its antineoplastic potential. "

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)