9-amino-alpha-noscapine

a synthetic antineoplastic; structure in first source

Also Known As:

(S)-3-((R)-9-amino-4-methoxy-6-methyl-5,6,7,8-tetrahydro(1,3) dioxolo(4,5-g)isoquinolin-5-yl)-6,7-dimethoxy isobenzo-furan-1(3H)-one; amino-noscapine

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Naik, Pradeep K: 2 articles (07/2014 - 05/2011)
2.	Askari, Vahid Reza: 1 article (11/2021)
3.	Nourbakhsh, Fahimeh: 1 article (11/2021)
4.	Qian, Yang: 1 article (04/2016)
5.	Qu, Hua-Jun: 1 article (04/2016)
6.	Santoshi, Seneha: 1 article (07/2014)
7.	Aneja, Ritu: 1 article (05/2011)
8.	Chandra, Ramesh: 1 article (05/2011)
9.	Chatterji, Biswa Prasun: 1 article (05/2011)
10.	Joshi, Harish C: 1 article (05/2011)

1.	Stroke (Strokes) 11/01/2021 - "Furthermore, recent studies have shown that noscapine and some analogues, like 9-bromonoscapine, amino noscapine, and 9-nitronoscapine, can be used to treat polycystic ovaries syndrome, stroke, and other diseases. "
2.	Neoplasms (Cancer) 04/01/2016 - "Amino-noscapine is a promising noscapine derivative undergoing R&D as an efficient anti-tumor drug. " 05/01/2011 - "Our results revealed that amino-noscapine has better anti-tumor activity than noscapine." 07/01/2014 - "More importantly, both amino-noscapine and its clinical derivative, bromo-noscapine have the highest binding affinity of -46.2 and -38.1 kcal/mol against αβIII (overexpression of αβIII has been associated with resistance to a wide range of chemotherapeutic drugs for several human malignancies) as measured using MM-PBSA. "

1.	Noscapine (Narcotine)
2.	9-nitronoscapine
3.	poly(tetramethylene succinate-co-tetramethylene adipate)