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1,2- distigmasterylhemisuccinoyl- glycero- 3- phosphocholine

an amphotericin B delivery agent; structure in first source

Also Known As:

1,2-distigmasterylhemisuccinoyl-sn-glycero-3-phosphocholine; DSHemsPC

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Alavizadeh, Seyedeh Hoda: 1 article (01/2017)
2.	Huang, Zhaohua: 1 article (01/2017)
3.	Iman, Maryam: 1 article (01/2017)
4.	Jaafari, Mahmoud R: 1 article (01/2017)
5.	Szoka, Francis C: 1 article (01/2017)

Related Diseases

1.	Leishmaniasis 01/01/2017 - "The results suggest that systemic DSHemsPC-AMB-Lip administration may be useful for the treatment of leishmaniasis, and because it costs less to produce DSHemsPC-AMB-Lip than AmBisome, DSHemsPC-AMB-Lip merits further investigation."
2.	Cutaneous Leishmaniasis 01/01/2017 - "In a model of the early lesions of cutaneous leishmaniasis (CL), the results indicated that the level of footpad inflammation was significantly (P < 0.001) lower in mice treated with DSHemsPC-AMB-Lip and AmBisome than mice treated with empty liposomes or 5% dextrose. "
3.	Inflammation (Inflammations) 01/01/2017 - "In a model of the early lesions of cutaneous leishmaniasis (CL), the results indicated that the level of footpad inflammation was significantly (P < 0.001) lower in mice treated with DSHemsPC-AMB-Lip and AmBisome than mice treated with empty liposomes or 5% dextrose. "
4.	Body Weight (Weight, Body) 01/01/2017 - "Multiple i.v. doses of the micellar formulation of AMB (Fungizone; 1 mg/kg of body weight), DSHemsPC-AMB-Lip (5 mg/kg), and AmBisome (5 mg/kg) were used in L. "

Related Drugs and Biologics

1.	liposomal amphotericin B
2.	Liposomes (Liposome)
3.	Glucose (Dextrose)
4.	Amphotericin B (Amphotericin)