HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

cucurbitacin IIa

antineoplastic from the medicinal plant Hemsleya amalils Diels; structure in first source

Also Known As:

Cuc IIa

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Cucurbitacins: 103
        cucurbitacin IIa: 3

Experts

1.	Cui, Xue: 1 article (01/2020)
2.	Li, Ying: 1 article (01/2020)
3.	Liu, Bo: 1 article (01/2020)
4.	Yang, Xinmei: 1 article (01/2020)
5.	Yao, Qingqiang: 1 article (01/2020)
6.	Yu, Kun: 1 article (01/2020)
7.	He, Jian: 1 article (05/2013)
8.	He, Xian-hui: 1 article (05/2013)
9.	Ouyang, Dong-yun: 1 article (05/2013)
10.	Qiao, Jing: 1 article (05/2013)

Related Diseases

1.	Gastroenteritis 05/01/2013 - "Cucurbitacin IIa (CuIIa), a member of cucurbitacin family, is isolated from the root of Hemsleya amabilis which has been used as an ancient remedy for bacillary dysentery and gastroenteritis. "
2.	Bacillary Dysentery (Shigellosis) 05/01/2013 - "Cucurbitacin IIa (CuIIa), a member of cucurbitacin family, is isolated from the root of Hemsleya amabilis which has been used as an ancient remedy for bacillary dysentery and gastroenteritis. "
3.	Neoplasms (Cancer) 01/22/2020 - "Synthesis of cucurbitacin IIa derivatives with apoptosis-inducing capabilities in human cancer cells." 03/01/2011 - "Cuc IIa is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3." 03/01/2011 - "Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation."

Related Drugs and Biologics

1.	Cucurbitacins
2.	Survivin