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OXM 6421

an oxyntomodulin analog

Also Known As:

OXM-6421; OXM6421

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - OXM 6421: 1
  - Gastrointestinal Hormones: 573
    - OXM 6421: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - OXM 6421: 1

Experts

1.	Baxter, J: 1 article (12/2010)
2.	Bloom, S R: 1 article (12/2010)
3.	Druce, M R: 1 article (12/2010)
4.	Field, B C T: 1 article (12/2010)
5.	Ford, H E: 1 article (12/2010)
6.	Ghatei, M A: 1 article (12/2010)
7.	Liu, Y-L: 1 article (12/2010)
8.	Minnion, J S: 1 article (12/2010)
9.	Murphy, K G: 1 article (12/2010)
10.	Shillito, J C: 1 article (12/2010)

Related Diseases

1.	Weight Loss (Weight Reduction) 12/01/2010 - "administration of OXM6421 for 21 days caused sustained weight loss in DIO mice. " 12/01/2010 - "In lean rats, daily subcutaneous (s.c.) administration of OXM6421 caused greater weight loss than the pair-fed animals, and a higher rate of oxygen consumption than both the pair-fed and the saline controls. " 12/01/2010 - "infusion of OXM6421 resulted in a significant weight loss, accompanied by an improvement in glucose homeostasis and an increase in circulating adiponectin levels. "
2.	Body Weight (Weight, Body) 12/01/2010 - "The chronic effect of OXM6421 on food intake, body weight and energy expenditure was examined in lean rats, and its anti-obesity potential was evaluated in DIO mice. " 12/01/2010 - "To determine the efficacy of a long-acting oxyntomodulin (OXM) analogue, OXM6421, in inhibiting food intake and decreasing body weight in lean and diet-induced obese (DIO) rodents. "
3.	Obesity 12/01/2010 - "OXM6421 induces negative energy balance in both lean and obese rodents, suggesting that long-acting OXM analogues may represent a potential therapy for obesity." 12/01/2010 - "The chronic effect of OXM6421 on food intake, body weight and energy expenditure was examined in lean rats, and its anti-obesity potential was evaluated in DIO mice. "

Related Drugs and Biologics

1.	Oxyntomodulin
2.	Adiponectin
3.	Glucose (Dextrose)

Related Therapies and Procedures

1.	Therapeutics