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rubropunctatin

an antineoplastic pigment isolated from Monascus; structure in first source

Networked: 7 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - rubropunctatin: 7
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - rubropunctatin: 7
    - Benzofurans: 26
      - rubropunctatin: 7

Experts

1.	Zheng, Yunquan: 4 articles (03/2020 - 09/2010)
2.	Guo, Yanghao: 3 articles (03/2016 - 09/2010)
3.	Shi, Xianai: 2 articles (11/2010 - 09/2010)
4.	Xin, Yanwen: 2 articles (11/2010 - 09/2010)
5.	Feng, Xiaolian: 1 article (03/2020)
6.	Ren, Zhenzhen: 1 article (03/2020)
7.	Xie, Jiming: 1 article (03/2020)
8.	Xu, Dongling: 1 article (03/2020)
9.	Yang, Jianming: 1 article (03/2020)
10.	Zhang, Xiaofang: 1 article (03/2020)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2023 - "Rubropunctatin, a metabolite isolated from the fungi of the genus Monascus, is a natural lead compound applied for the suppression of tumors with good anti-cancer activity. " 03/06/2020 - "Therefore, liposomal nanoparticles have great potential as drug delivery vehicles of Rubropunctatin for cancer treatment." 11/01/2010 - "Rubropunctatin has potential to be developed as a new natural anti-cancer agent." 11/01/2010 - "Anti-cancer effect of rubropunctatin against human gastric carcinoma cells BGC-823." 03/30/2016 - "Monascus Pigment Rubropunctatin: A Potential Dual Agent for Cancer Chemotherapy and Phototherapy."
2.	Carcinoma (Carcinomatosis) 03/30/2016 - "The Monascus pigment, rubropunctatin, was extracted and purified from red mold rice (RMR), and its cytotoxic activities against human cervical carcinoma HeLa cells were studied under the conditions with or without light irradiation. " 11/01/2010 - "Anti-cancer effect of rubropunctatin against human gastric carcinoma cells BGC-823."
3.	Stomach Neoplasms (Stomach Cancer) 09/08/2010 - "The inhibition effect of rubropunctatin was higher than that of taxol on the growth of the human gastric cancer cell SH-SY5Y (P<0.05), BGC-823 (P<0.01), AGS (P<0.01), and MKN45 (P<0.05). "
4.	Inflammation (Inflammations) 02/09/2005 - "Six azaphilones, monascin (1), ankaflavin (2), rubropunctatin (3), monascorburin (4), rubropunctamine (5), and monascorburamine (6), two furanoisophthalides, xanthomonasin A (7) and xanthomonasin B (8), and two amino acids, (+)-monascumic acid (9) and (-)-monascumic acid (10), isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice) were evaluated for their inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, on the induction of Epstein-Barr virus early antigen (EBV-EA) by TPA in Raji cells, and on the activation of (+/-)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor. "
5.	Breast Neoplasms (Breast Cancer) 07/01/2023 - "CCK-8 assays revealed that lecithin/chitosan nanoparticles loaded with rubropunctatin (RCP-NPs) had significantly enhanced cytotoxicity against mouse mammary cancer 4T1 cells. "

Related Drugs and Biologics

1.	Lecithins
2.	Chitosan
3.	Drug Carriers
4.	Paclitaxel (Taxol)
5.	Polyketides
6.	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)
7.	Sincalide
8.	Nitric Oxide (Nitrogen Monoxide)
9.	Cisplatin (Platino)
10.	Amino Acids

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Phototherapy (Light Therapy)