poly(2,6- (4,4- bis(2- ethylhexyl)- 4H- cyclopenta(2,1- b- 3,4- b0)dithiophene))- alt- 4,7- (2,1,3- benzothiadiazole)

structure in first source

Also Known As:

PCPDTBT

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - poly(2,6-(4,4-bis(2-ethylhexyl)-4H-cyclopenta(2,1-b-3,4-b0)dithiophene))-alt-4,7-(2,1,3-benzothiadiazole): 5
Biomedical and Dental Materials
- Polymers: 13051
  - poly(2,6-(4,4-bis(2-ethylhexyl)-4H-cyclopenta(2,1-b-3,4-b0)dithiophene))-alt-4,7-(2,1,3-benzothiadiazole): 5
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - poly(2,6-(4,4-bis(2-ethylhexyl)-4H-cyclopenta(2,1-b-3,4-b0)dithiophene))-alt-4,7-(2,1,3-benzothiadiazole): 5
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Thiadiazoles: 99
      - poly(2,6-(4,4-bis(2-ethylhexyl)-4H-cyclopenta(2,1-b-3,4-b0)dithiophene))-alt-4,7-(2,1,3-benzothiadiazole): 5
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Thiadiazoles: 99
        poly(2,6-(4,4-bis(2-ethylhexyl)-4H-cyclopenta(2,1-b-3,4-b0)dithiophene))-alt-4,7-(2,1,3-benzothiadiazole): 5

Experts

1.	Sun, Yidan: 1 article (01/2021)
2.	Wang, Jinfang: 1 article (01/2021)
3.	Wang, Yuqi: 1 article (01/2021)
4.	Wu, Luyan: 1 article (01/2021)
5.	Ye, Deju: 1 article (01/2021)
6.	Zeng, Wenhui: 1 article (01/2021)
7.	Crossley, Daniel L: 1 article (12/2019)
8.	Dailey, Lea Ann: 1 article (12/2019)
9.	Green, Mark: 1 article (12/2019)
10.	Ingleson, Michael: 1 article (12/2019)

Related Diseases

1.	Neoplasms (Cancer) 12/18/2019 - "In a mouse tumor xenograft model, P4 nanoparticles showed a 5-fold higher SBR than PCPDTBT particles with fluorophore accumulation in the liver > spleen > tumor. " 01/01/2021 - "Under excitation at 660 nm, SPN-MMP-RGD shows "always-on" fluorescence of PCPDTBT (830 nm) and activatable fluorescence of Cy5.5 (690 nm) toward MMP-2, affording a remarkable ≈176-fold enhancement in fluorescence intensity ratio between 690 and 830 nm (I690 /I830 ) for sensitive detection of MMP-2 activity in vitro and in tumor cells. " 10/20/2017 - "These micelles, with excellent water dispersibility, comprises of three distinct functional components: (1) the monomethoxy-poly(ethylene glycol)-S-S-hexadecyl (mPEG-S-S-C16), which forms the micelles, can render hydrophobic substances water-soluble and improve the colloidal stability; (2) disulfide linkages can be cleaved in a reductive environment for tumor specific drug release due to the high GSH concentrations of tumor micro-environment; (3) PCPDTBT dots and anti-cancer drug DOX that are loaded inside the hydrophobic core of the micelle can be applied to simultaneously perform PTT and chemotherapy to achieve significantly enhanced tumor killing efficiency both in vitro and in vivo. "
2.	Bacterial Infections (Bacterial Infection) 01/01/2022 - "Herein, we report the development of a near-infrared (NIR) chemiluminescent (CL) nanoparticles ALPBs containing luminol, AIE dye (TTDC), PCPDTBT, and nitric oxide (NO) donor (BNN6), which could achieve a deep CL imaging-guided photothermal-NO gas therapy of bacterial infection. "
3.	Hypoxia (Hypoxemia) 01/01/2022 - "Under NIR irradiation, photothermal therapy and photodynamic therapy derived from PCPDTBT, hypoxia-activated chemotherapy derived from tirapazamine, and RNAi derived from siMcl-1 were used for the combined treatment for RA by killing activated macrophages. "

Related Drugs and Biologics

1.	Matrix Metalloproteinases (MMPs)
2.	Nitric Oxide (Nitrogen Monoxide)
3.	Micelles
4.	Luminol
5.	Coloring Agents (Dyes)
6.	Disulfides
7.	Tirapazamine (SR 4233)
8.	CY5.5 cyanine dye
9.	monomethoxy-poly(ethylene glycol)-S-S-hexadecyl

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics
3.	Photochemotherapy (Photodynamic Therapy)
4.	Photothermal Therapy