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4-(phenylthio)butanoic acid

structure in first source

Also Known As:

4-(phenylthio)butryic acid; PTBA acid

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hukriede, Neil A: 3 articles (01/2022 - 01/2016)
2.	Davidson, Alan J: 2 articles (01/2022 - 01/2019)
3.	Espiritu, Eugenel B: 2 articles (01/2022 - 01/2019)
4.	McDaniels, Michael D: 2 articles (01/2022 - 01/2019)
5.	Vernetti, Lawrence A: 2 articles (01/2022 - 01/2016)
6.	Baty, Catherine J: 1 article (01/2022)
7.	Crunk, Amanda E: 1 article (01/2022)
8.	Emlet, Dave R: 1 article (01/2022)
9.	Happ, Cassandra L: 1 article (01/2022)
10.	Kellum, John A: 1 article (01/2022)

Related Diseases

1.	Fibrosis (Cirrhosis) 01/01/2019 - "Previously, we identified 4-(phenylthio)butanoic acid (PTBA), a histone deacetylase inhibitor (HDI), as an enhancer of renal recovery, and showed that PTBA treatment increased RTEC proliferation and reduced renal fibrosis. " 01/01/2022 - "Finally, we show that 4-(phenylthio)butanoic acid, an HDAC inhibitor with anti-fibrotic effects in vivo, reduces hemin-induced human kidney organoid fibrosis. "
2.	Ischemia 01/01/2016 - "Using a phenotypic screen in zebrafish, we identified 4-(phenylthio)butanoic acid (PTBA), which promotes proliferation of embryonic kidney progenitor cells (EKPCs), and the PTBA methyl ester UPHD25, which also increases postinjury repair in ischemia-reperfusion and aristolochic acid-induced AKI in mice. "

Related Drugs and Biologics

1.	Histone Deacetylase Inhibitors
2.	Hemin (Panhematin)
3.	Esters
4.	aristolochic acid I (aristolochic acid)