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3- (2- chloro- 6- fluorobenzyl)- imidazolidine- 2,4- dione

analgesic; structure in first source

Also Known As:

PT-31 cpd

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Imidazolidines: 39
        3-(2-chloro-6-fluorobenzyl)-imidazolidine-2,4-dione: 1

Experts

1.	Antonio, Camila Boque: 1 article (10/2019)
2.	Betti, Andresa Heemann: 1 article (10/2019)
3.	Herzfeldt, Vivian: 1 article (10/2019)
4.	Pitta, Marina Galdino da Rocha: 1 article (10/2019)
5.	Rates, Stela Maris Kuze: 1 article (10/2019)
6.	Vaudry, David: 1 article (10/2019)
7.	da Rocha Pitta, Ivan: 1 article (10/2019)
8.	do Rego, Jean-Claude: 1 article (10/2019)
9.	do Rego, Jean-Luc: 1 article (10/2019)

Related Diseases

1.	Neurobehavioral Manifestations 10/01/2019 - "In this study, a new imidazolidine derivative 3-(2-chloro-6-fluorobenzyl)-imidazolidine-2,4-dione, PT-31, a putative α2A-adrenoceptor agonist, was evaluated in mouse models predictive of efficacy in the treatment of positive and cognitive symptoms of schizophrenia, as well as its ability to promote cerebellar granule cell survival in vitro, in the presence or absence of glutamate (100 µmol/l). "
2.	Schizophrenia (Dementia Praecox) 10/01/2019 - "In this study, a new imidazolidine derivative 3-(2-chloro-6-fluorobenzyl)-imidazolidine-2,4-dione, PT-31, a putative α2A-adrenoceptor agonist, was evaluated in mouse models predictive of efficacy in the treatment of positive and cognitive symptoms of schizophrenia, as well as its ability to promote cerebellar granule cell survival in vitro, in the presence or absence of glutamate (100 µmol/l). "

Related Drugs and Biologics

1.	Imidazolidines
2.	Glutamic Acid (Glutamate)