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3- (4- bromophenyl)- 6- nitrobenzo(1.3.2)dithiazolium ylide 1,1-dioxide

a COX-2 inhibitor and antineoplastic agent; structure in first source

Also Known As:

3-BPN-D-D cpd; CX 9051; CX-9051; CX9051

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Cyclic S-Oxides
    - 3-(4-bromophenyl)-6-nitrobenzo(1.3.2)dithiazolium ylide 1,1-dioxide: 1
Heterocyclic Compounds: 198

Experts

1.	Chen, Grace Shiahuy: 1 article (08/2010)
2.	Chern, Ji-Wang: 1 article (08/2010)
3.	Guh, Jih-Hwa: 1 article (08/2010)
4.	Huang, Chiung-Hua: 1 article (08/2010)
5.	Lu, Pin-Hsuan: 1 article (08/2010)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 08/01/2010 - "Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: the roles of NF-kappaB and crosstalk between the extrinsic and intrinsic apoptotic pathways."
2.	Neoplasms (Cancer) 08/01/2010 - "Taken together, our data suggest that CX9051 induces TRAIL up-regulation and activation of extrinsic apoptotic signaling, which in turn activates mitochondria-mediated intrinsic apoptotic signaling, leading to cancer cell apoptosis." 08/01/2010 - "We now show that CX9051 inhibits cell proliferation and induces apoptosis in numerous human cancer cell types. "

Related Drugs and Biologics

1.	Cyclooxygenase Inhibitors
2.	NF-kappa B (NF-kB)