A hereditary condition where patients present with cutaneous LEIOMYOMAS (female patients may also have uterine leiomyomas) and are at increased risk for developing KIDNEY NEOPLASMS. Tumors initally appear during adulthood on the skin of the torso, arms, legs, and face and increase in size and number over time; 10% to 16% of patients develop RENAL CELL CARCINOMA. A heterozygous germline mutation in the FH gene has been identified. OMIM: 150800
Also Known As:
Cutaneous leiomyomata with uterine leiomyomata; Leiomyoma, hereditary multiple, of skin; Leiomyoma, multiple cutaneous; Leiomyomatosis and renal cell cancer, hereditary; Multiple cutaneous and uterine leiomyomata 1; Multiple cutaneous and uterine leiomyomatosis; Reed's syndrome