5,7- dihydroxy- 3- (3- hydroxy- 4- methoxybenzyl)- 6- methoxychroman- 4- one

a homoisoflavone with antiangiogenesis activity

Also Known As:

5,7-dihydroxy-HMBMC; cremastranone

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Isoflavones: 2663
        5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one: 5
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Isoflavones: 2663
        5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one: 5

Experts

1.	Basavarajappa, Halesha D: 2 articles (06/2015 - 10/2014)
2.	Corson, Timothy W: 2 articles (06/2015 - 10/2014)
3.	Lee, Bit: 2 articles (06/2015 - 10/2014)
4.	Seo, Seung-Yong: 2 articles (06/2015 - 10/2014)
5.	Sulaiman, Rania S: 2 articles (06/2015 - 10/2014)
6.	An, Hongchan: 1 article (06/2015)
7.	Kim, Eun-Yeong: 1 article (06/2015)
8.	Lee, Hyungjun: 1 article (06/2015)
9.	Lee, Kiho: 1 article (06/2015)
10.	Magaña, Carlos: 1 article (06/2015)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 11/01/2022 - "In this study, we synthesized six homoisoflavane derivatives of cremastranone and investigated their cytotoxic effects on the human colorectal cancer cell lines HCT116 and LoVo. " 01/01/2023 - "Erratum to "Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis" [Biomol. " 11/01/2022 - "Therefore, the synthesized cremastranone derivatives could be applied as novel therapeutic agents against colorectal cancer." 11/01/2022 - "Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis."
2.	Neoplasms (Cancer) 09/01/2023 - "In this study, we investigated the anti-cancer effect of synthetic homoisoflavane derivatives of cremastranone on breast cancer cells. "
3.	Breast Neoplasms (Breast Cancer) 09/01/2023 - "In this study, we investigated the anti-cancer effect of synthetic homoisoflavane derivatives of cremastranone on breast cancer cells. " 09/01/2023 - "Cremastranone-Derived Homoisoflavanes Suppress the Growth of Breast Cancer Cells via Cell Cycle Arrest and Caspase-Independent Cell Death."
4.	Choroidal Neovascularization 06/25/2015 - "Cremastranone is an antiangiogenic, naturally occurring homoisoflavanone with efficacy in retinal and choroidal neovascularization models and antiproliferative selectivity for endothelial cells over other cell types. "
5.	Pathologic Neovascularization 10/21/2014 - "Synthetic cremastranone inhibited the proliferation, migration and tube formation ability of human retinal microvascular endothelial cells, important steps in pathological angiogenesis. "

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