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CP-809,101

a selective 5-HT2C agonist that shows antipsychotic activity in animal models; structure in first source

Also Known As:

2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrazines: 150
    - CP-809,101: 3
  - Piperazines: 26
    - CP-809,101: 3

Experts

1.	Chiang, Phoebe: 2 articles (06/2007 - 02/2007)
2.	Bromek, Ewa: 1 article (12/2019)
3.	Daniel, Władysława A: 1 article (12/2019)
4.	Haduch, Anna: 1 article (12/2019)
5.	Rysz, Marta: 1 article (12/2019)
6.	Aubrecht, Jiri: 1 article (06/2007)
7.	Cheung, Jennifer R: 1 article (06/2007)
8.	Coelho, Richard V: 1 article (06/2007)
9.	Coffing, Stephanie L: 1 article (06/2007)
10.	Dalvie, Deepak K: 1 article (06/2007)

Related Diseases

1.	Obesity 06/01/2007 - "2-(3-Chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine (3) is a potent and selective 5-HT(2C) agonist that exhibits dose-dependent inhibition of food intake and reduction in body weight in rats, making it an attractive candidate for treatment of obesity. "
2.	Catalepsy 02/01/2007 - "At doses up to 56 mg/kg, CP-809,101 did not produce catalepsy. "
3.	Body Weight (Weight, Body) 06/01/2007 - "2-(3-Chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine (3) is a potent and selective 5-HT(2C) agonist that exhibits dose-dependent inhibition of food intake and reduction in body weight in rats, making it an attractive candidate for treatment of obesity. "
4.	AIDS-Related Complex (ARC) 12/01/2019 - "The 5-HT2C serotonin receptor agonist CP-809,101 was injected into the ARC for 5 days. " 12/01/2019 - "In rats receiving an injection of the 5-HT2C serotonin receptor agonist CP-809,101 into the ARC (1 μg/side) for five days, the activities of CYP2B, CYP2C11 and CYP3A significantly increased corresponding with the elevated enzyme protein level. "

Related Drugs and Biologics

1.	Cytochrome P-450 CYP3A
2.	5-HT2C Serotonin Receptor
3.	Proteins (Proteins, Gene)
4.	Enzymes