HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
phenylethynylbenzenesulfonamide
structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Sulfonamides: 2809
Benzenesulfonamides: 153
phenylethynylbenzenesulfonamide: 1
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzenesulfonamides: 153
phenylethynylbenzenesulfonamide: 1
Sulfur Compounds: 278
Sulfones: 534
Sulfonamides: 2809
Benzenesulfonamides: 153
phenylethynylbenzenesulfonamide: 1
Experts
1.
Innocenti, Alessio
: 1 article (10/2011)
2.
Knaus, Edward E
: 1 article (10/2011)
3.
Scozzafava, Andrea
: 1 article (10/2011)
4.
Supuran, Claudiu T
: 1 article (10/2011)
Related Diseases
1.
Neoplasms (Cancer)
10/01/2011 - "
A series of compounds incorporating regioisomeric phenylethynylbenzenesulfonamide moieties has been investigated for the inhibition of four human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, hCA I, II, IX and XII. Inhibition between the low nanomolar to the milliomolar range has been observed against them, with several low nanomolar and tumor-CA selective inhibitors detected.
"
10/01/2011 - "
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
"
Related Drugs and Biologics
1.
Protein Isoforms (Isoforms)
2.
Carbonic Anhydrases (Carbonic Anhydrase)