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SSR 146977

a tachykinin NK3 receptor antagonist; structure in first source

Also Known As:

(R)-(N)-(1-(3-(1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl)propyl)-4-phenylpiperidin-4-yl)-N-dimethylurea

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 140
- Amides: 2487
  - Urea: 15387
    - Methylurea Compounds
      - SSR 146977: 1
Heterocyclic Compounds: 207
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - SSR 146977: 1

Experts

1.	Advenier, Charles: 1 article (05/2002)
2.	Daoui, Samira: 1 article (05/2002)
3.	Emonds-Alt, Xavier: 1 article (05/2002)
4.	Gueudet, Christiane: 1 article (05/2002)
5.	Le Fur, Gérard: 1 article (05/2002)
6.	Maffrand, Jean-Pierre: 1 article (05/2002)
7.	Michaud, Jean-Claude: 1 article (05/2002)
8.	Naline, Emmanuel: 1 article (05/2002)
9.	Oury-Donat, Florence: 1 article (05/2002)
10.	Pascal, Marc: 1 article (05/2002)

Related Diseases

1.	Hypersensitivity (Allergy) 05/01/2002 - "In vivo, in the respiratory system, SSR 146977 inhibited bronchial hyperresponsiveness to acetylcholine, bronchial microvascular permeability hypersensitivity to histamine (doses of 0.1-1 mg/kg i.p.), and cough (doses of 0.03-1 mg/kg i.p.) provoked by citric acid in guinea pigs. "
2.	Cough 05/01/2002 - "In vivo, in the respiratory system, SSR 146977 inhibited bronchial hyperresponsiveness to acetylcholine, bronchial microvascular permeability hypersensitivity to histamine (doses of 0.1-1 mg/kg i.p.), and cough (doses of 0.03-1 mg/kg i.p.) provoked by citric acid in guinea pigs. "

Related Drugs and Biologics

1.	Citric Acid (Citrate)
2.	Histamine (Histamine Dihydrochloride)
3.	Acetylcholine (Acetylcholine Chloride)