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3-methylglutamic acid

Also Known As:

NCI-41356; threo-3-methylglutamic acid

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675

Experts

1.	Cai, Jun: 1 article (05/2014)
2.	Chen, Zhijuan: 1 article (05/2014)
3.	Han, Song: 1 article (05/2014)
4.	Jiang, Huabei: 1 article (05/2014)
5.	Jiang, Wenguo: 1 article (05/2014)
6.	Ostrov, David A: 1 article (05/2014)
7.	Ruan, Qing: 1 article (05/2014)
8.	Xi, Lei: 1 article (05/2014)

Related Diseases

1.	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/24/2023 - "Here, we have explored whether NCI-41356, a chemical inhibitor of HSPB5, can limit the development of pulmonary fibrosis. " 01/24/2023 - "In this study, we determined that inhibition of HSPB5 by NCI-41356 could limit pulmonary fibrosis in mice by limiting the synthesis of collagen and pro-fibrotic markers. "
2.	Fibrosis (Cirrhosis) 01/24/2023 - "In vitro, we studied the specific role of NCI-41356 on the chaperone function of HSPB5 and the inhibitory properties of NCI-41356 on HSPB5 interaction with its partner SMAD4 during fibrosis. " 01/24/2023 - "HSPB5 Inhibition by NCI-41356 Reduces Experimental Lung Fibrosis by Blocking TGF-β1 Signaling."
3.	Breast Neoplasms (Breast Cancer) 05/01/2014 - "Intraperitoneal injection of NCI-41356 greatly inhibits the tumour growth and vasculature development in in vivo human breast cancer xenograft models. " 05/01/2014 - "The observed in vitro anti-tumour angiogenesis of endothelial cells might be attributed to the down-regulation of paracrine VEGF signalling in the breast cancer cells after treatment with NCI-41356. "

Related Drugs and Biologics

1.	Collagen
2.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)

Related Therapies and Procedures

1.	Intraperitoneal Injections
2.	Aftercare (After-Treatment)