4-dioxan-10-one 2H,3H,6aH- pyrrolidino(2'',1''- 3',2')1,3- oxazino(6',5'- 5,4)benzo(e)1 (CX 614)

an ampakine (AMPA receptor modulator); structure in first source

Also Known As:

CX 614; CX614; 2H,3H,6aH-pyrrolidino(2'',1''-3',2')1,3-oxazino(6',5'-5,4)benzo(e)1, 4-dioxan-10-one; 2,3,6a,7,8,9-hexahydro-11H-(1,4)dioxino(2,3-g)pyrrolo(2,1-b)(1,3)benzoxazin-11-one; BDP 37; BDP-37; CX-614

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - 4-dioxan-10-one 2H,3H,6aH-pyrrolidino(2'',1''-3',2')1,3-oxazino(6',5'-5,4)benzo(e)1: 3

Experts

1.	Lippa, Arnold S: 1 article (01/2018)
2.	Purcell, Richard: 1 article (01/2018)
3.	Radin, Daniel P: 1 article (01/2018)
4.	Bhadra, Mohitosh: 1 article (05/2014)
5.	Dutta, Uttam: 1 article (05/2014)
6.	Kancherla, Rajesh: 1 article (05/2014)
7.	Maiti, Debabrata: 1 article (05/2014)
8.	Maity, Soham: 1 article (05/2014)
9.	Mobin, Shaikh M: 1 article (05/2014)
10.	Modak, Atanu: 1 article (05/2014)

Related Diseases

1.	Parkinson Disease (Parkinson's Disease) 01/01/2023 - "Ampakine CX614 increases respiratory rate in a mouse model of Parkinson's disease."
2.	Neoplasms (Cancer) 01/01/2018 - "CX614 inhibits the growth of multiple cancers in vitro and bolsters the oncolytic activity of FLX in several cancers." 01/01/2018 - "Likewise, CX614 inhibits cancer cell viability in a dose-dependent fashion and its combination with FLX synergistically reduces cell viability. "
3.	Alzheimer Disease (Alzheimer's Disease) 05/16/2014 - "The method provides a convenient synthesis of an investigational new medicine CX-614, which has potential in finding treatment for Parkinson's and Alzheimer's diseases. "