1,N(6)-etheno-2'-deoxyadenosine

structure in first source

Also Known As:

N6-ED-adenosine

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        Deoxyadenosines: 1
        1,N(6)-etheno-2'-deoxyadenosine: 3
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - Deoxyadenosines: 1
        1,N(6)-etheno-2'-deoxyadenosine: 3
  - Deoxyribonucleosides: 34
    - Deoxyadenosines: 1
      - 1,N(6)-etheno-2'-deoxyadenosine: 3

Experts

1.	Chen, Hauh-Jyun Candy: 1 article (11/2011)
2.	Lin, Wen-Peng: 1 article (11/2011)
3.	Banaszkiewicz, Zbigniew: 1 article (09/2010)
4.	Bartsch, Helmut: 1 article (09/2010)
5.	Cadet, Jean: 1 article (09/2010)
6.	Chaber, Andrzej: 1 article (09/2010)
7.	Cieśla, Jarosław M: 1 article (09/2010)
8.	Douki, Thierry: 1 article (09/2010)
9.	Gackowski, Daniel: 1 article (09/2010)
10.	Janik, Justyna: 1 article (09/2010)

Related Diseases

1.	Carcinogenesis 09/15/2010 - "To assess the role of lipid peroxidation-induced DNA damage and repair in colon carcinogenesis, the excision rates and levels of 1,N(6)-etheno-2'-deoxyadenosine (epsilondA), 3,N(4)-etheno-2'-deoxycytidine (epsilondC), and 1,N(2)-etheno-2'-deoxyguanosine (1,N(2)-epsilondG) were analyzed in polymorphic blood leukocytes (PBL) and resected colon tissues of 54 colorectal carcinoma (CRC) patients and PBL of 56 healthy individuals. "
2.	Colorectal Neoplasms (Colorectal Cancer) 09/15/2010 - "To assess the role of lipid peroxidation-induced DNA damage and repair in colon carcinogenesis, the excision rates and levels of 1,N(6)-etheno-2'-deoxyadenosine (epsilondA), 3,N(4)-etheno-2'-deoxycytidine (epsilondC), and 1,N(2)-etheno-2'-deoxyguanosine (1,N(2)-epsilondG) were analyzed in polymorphic blood leukocytes (PBL) and resected colon tissues of 54 colorectal carcinoma (CRC) patients and PBL of 56 healthy individuals. "
3.	Neoplasms (Cancer) 11/15/2011 - "Exocyclic DNA adducts, including 1,N(2)-propano-2'-deoxyguanosine derived from acrolein (AdG) and crotonaldehyde (CdG) and the three lipid peroxidation-related etheno adducts 1,N(6)-etheno-2'-deoxyadenosine (εdAdo), 3,N(4)-etheno-2'-deoxycytidine (εdCyt), and 1,N(2)-etheno-2'-deoxyguanosine (1,N(2)-εdGuo), play an important role in cancer formation and they are associated with oxidative-stress-induced DNA damage. "
4.	Inflammation (Inflammations) 01/01/2008 - "To overcome these problems, we developed a general and sensitive liquid chromatographic tandem mass spectrometry (LC/MS-MS) method to quantify, in a single DNA sample, the nucleoside forms of seven DNA lesions reflecting the range of chemistries associated with inflammation: 2'-deoxyuridine, 2'-deoxyxanthosine and 2'-deoxyinosine from nitrosative deamination; 8-oxo-2'-deoxyguanosine from oxidation; and 1,N(2)-etheno-2'-deoxyguanosine, 1,N(6)-etheno-2'-deoxyadenosine and 3,N(4)-etheno-2'-deoxycytidine arising from reaction of DNA with lipid peroxidation products. "

Related Drugs and Biologics

1.	3,N(4)-ethenodeoxycytidine
2.	DNA Adducts
3.	Nucleosides
4.	DNA (Deoxyribonucleic Acid)
5.	Acrolein (Aqualin)
6.	8-Hydroxy-2'-Deoxyguanosine
7.	2'-deoxyxanthosine
8.	2-butenal (crotonaldehyde)
9.	deoxyinosine