isopimaric acid

isolated from the bark of Illicium jadifengpi

Also Known As:

4-epi-isopimaric acid; 1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,7S)-

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Phenanthrenes: 27
        isopimaric acid: 4
- Carboxylic Acids: 973
  - isopimaric acid: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Phenanthrenes: 27
    - isopimaric acid: 4

Experts

1.	Chen, Yu-Xiang: 1 article (06/2021)
2.	Gu, Yan: 1 article (06/2021)
3.	Lu, Yan-Ju: 1 article (06/2021)
4.	Wang, Jing: 1 article (06/2021)
5.	Xu, Shi-Chao: 1 article (06/2021)
6.	Zhao, Zhen-Dong: 1 article (06/2021)
7.	Eichenauer, Elisabeth: 1 article (10/2020)
8.	Glasl, Sabine: 1 article (10/2020)
9.	Goels, Thomas: 1 article (10/2020)
10.	Heiss, Elke H: 1 article (10/2020)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 06/01/2021 - "Compound isopimaric acid (5-bromo pyridine-2-formaldehyde) acylhydrazone exhibited a significant antitumorial activity against hepatocarcioma cells (HepG-2) and breast cancer cells (MDA-MB-231), with inhibition degrees of 74.21% and 70.39%, respectively, at 100 μM.[Formula: see text]." 01/01/2023 - "In this study, We analyzed the effects and mechanisms of isopimaric acid (IPA), an ion channel regulator, on the proliferation and metastasis of breast cancer cells (4 T1, MDA-MB-231and MCF-7) by cell functional assay, flow cytometry, western blot, proteomics and other techniques in vitro and in vivo. " 01/01/2023 - "Isopimaric acid, an ion channel regulator, regulates calcium and oxidative phosphorylation pathways to inhibit breast cancer proliferation and metastasis."
2.	Neoplasm Metastasis (Metastasis) 01/01/2023 - "In this study, We analyzed the effects and mechanisms of isopimaric acid (IPA), an ion channel regulator, on the proliferation and metastasis of breast cancer cells (4 T1, MDA-MB-231and MCF-7) by cell functional assay, flow cytometry, western blot, proteomics and other techniques in vitro and in vivo. " 01/01/2023 - "Isopimaric acid, an ion channel regulator, regulates calcium and oxidative phosphorylation pathways to inhibit breast cancer proliferation and metastasis."
3.	Wounds and Injuries (Trauma) 10/01/2020 - "Pinoresinol, DHAA, three of its hydroxylated derivatives, and pimaric and isopimaric acid as well as defined combinations of the hydroxylated DHAA derivatives led to a significantly enhanced wound closure by up to 90% at concentrations between 1 and 10 µM. "
4.	Rubella (German Measles) 01/01/2023 - "Results: Two diterpenoid molecules, 14α-hydroxyisopimaric acid (C069002) and isopimaric acid (C069004), extracted from the flowers of Callicarpa rubella Lindl., significantly attenuated ox-LDL-induced foam cell formation in RAW264.7 macrophages. "

Related Drugs and Biologics

1.	Ion Channels (Ion Channel)
2.	Diterpenes
3.	Calcium
4.	Acids
5.	pinoresinol
6.	oxidized low density lipoprotein