sulochrin

RN refers to methyl ester; from culture filtrate of Penicillium sp; structure in first source

Also Known As:

methyl 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoate; benzoic acid, 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-, methyl ester

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        sulochrin: 3
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - sulochrin: 3

Experts

1.	El-Kashef, Dina H: 1 article (01/2021)
2.	Frank, Marian: 1 article (01/2021)
3.	Lin, Wenhan: 1 article (01/2021)
4.	Liu, Zhen: 1 article (01/2021)
5.	Müller, Werner E G: 1 article (01/2021)
6.	Proksch, Peter: 1 article (01/2021)
7.	Reimche, Irene: 1 article (01/2021)
8.	Teusch, Nicole: 1 article (01/2021)
9.	Youssef, Fadia S: 1 article (01/2021)
10.	Aizaki, Hideki: 1 article (11/2013)

Related Diseases

1.	Lymphoma (Lymphomas) 01/01/2021 - "In vitro cytotoxic assessment using MTT assay showed that sulochrin (9) exhibited cytotoxic activity versus L5178Y mouse lymphoma cells with an IC50 value of 5.1 µM and inhibition of migration of MDA-MB 231 breast cancer cells at a concentration of 70 µM."
2.	Inflammation (Inflammations) 10/01/1998 - "To evaluate the capacity of a novel compound, sulochrin, as an inhibitor of eosinophilic inflammation, we examined the effects of this compound on various effector functions of eosinophils. "
3.	Infections 11/01/2013 - "Sulochrin inhibited HCV infection in a dose-dependent manner without any apparent cytotoxicity up to 50 μM. " 11/01/2013 - "A cell-based functional screening of the library identified sulochrin as a compound that decreased HCV infectivity in a multi-round HCV infection assay. "
4.	Breast Neoplasms (Breast Cancer) 01/01/2021 - "In vitro cytotoxic assessment using MTT assay showed that sulochrin (9) exhibited cytotoxic activity versus L5178Y mouse lymphoma cells with an IC50 value of 5.1 µM and inhibition of migration of MDA-MB 231 breast cancer cells at a concentration of 70 µM."