UDP-3-O-acyl-N-acetylglucosamine deacetylase

permeability and cell division gene product that catalyzes deacetylation in second enzymatic step of Lipid A biosynthesis; do not confuse with EnvA protein from Chlamydia psittaci

Also Known As:

EnvA protein, E coli; LpxC protein, E coli; UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase; UDP-3-O-acyl-N-acetylglucosamine deacetylase, E coli

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Amidohydrolases: 43
      - UDP-3-O-acyl-N-acetylglucosamine deacetylase: 1

Experts

1.	Feng, Dongxiao: 1 article (01/2018)
2.	Jarvis, Gary A: 1 article (01/2018)
3.	John, Constance M: 1 article (01/2018)

Related Diseases

1.	Infections 01/01/2018 - "Inhibitors of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), which catalyses the second step in the biosynthesis of lipid A, have been developed as potential antibiotics for Gram-negative infections. "

Related Drugs and Biologics

1.	Lipid A
2.	Anti-Bacterial Agents (Antibiotics)