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mussaendoside O
isolated from the Chinese herb Mussaenda pubescens; structure in first source
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycosides: 2119
Saponins: 2867
mussaendoside O: 1
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Triterpenes: 2493
mussaendoside O: 1
Related Diseases
1.
Bone Resorption
10/01/2022 - "
Mussaendoside O attenuates OC differentiation in vitro and LPS-induced bone resorption in a mouse model by inhibiting the RANKL-activated c-Fos/NFATc1 signaling pathways.
"
10/01/2022 - "
Mice orally administrated with mussaendoside O exhibited significant protection from LPS-induced bone resorption and OC formation.
"
10/01/2022 - "
The effects of mussaendoside O on LPS-induced bone resorption in a mouse model were evaluated using micro-CT and immunohistochemical staining.
"
10/01/2022 - "
This study was aimed to investigate the effect of mussaendoside O, an NTCS isolated from Mussaenda pubescens, on RANKL-induced OC differentiation and its underlying mechanism in vitro, and lipopolysaccharide (LPS)-induced bone resorption in a mouse model.
"
2.
Bone Diseases (Bone Disease)
10/01/2022 - "
Therefore, mussaendoside O may be a valuable lead compound for preventing or treating of osteolytic bone diseases.
"
Related Drugs and Biologics
1.
Lipopolysaccharides