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lissamine rhodamine-sulfonylamidosphingosyl beta-glucoside

used for estimating beta-glucosidase activity in vitro in the absence of detergents to subtype Gaucher disease variants

Also Known As:

LRO-GC

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Ceramides: 4082
    - Cerebrosides: 106
      - Glucosylceramides: 763
        lissamine rhodamine-sulfonylamidosphingosyl beta-glucoside: 1
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycolipids: 2799
    - Glycosphingolipids: 1659
      - Neutral Glycosphingolipids: 101
        Ceramides: 4082
        Cerebrosides: 106
        Glucosylceramides: 763
        lissamine rhodamine-sulfonylamidosphingosyl beta-glucoside: 1
Lipids: 114793
- Glycolipids: 2799
  - Glycosphingolipids: 1659
    - Neutral Glycosphingolipids: 101
      - Ceramides: 4082
        Cerebrosides: 106
        Glucosylceramides: 763
        lissamine rhodamine-sulfonylamidosphingosyl beta-glucoside: 1
- Membrane Lipids: 1591
  - Sphingolipids: 3208
    - Glycosphingolipids: 1659
      - Neutral Glycosphingolipids: 101
        Ceramides: 4082
        Cerebrosides: 106
        Glucosylceramides: 763
        lissamine rhodamine-sulfonylamidosphingosyl beta-glucoside: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Rhodamines: 466
        lissamine rhodamine-sulfonylamidosphingosyl beta-glucoside: 1

Related Diseases

1.	Gaucher Disease (Gaucher's Disease) 09/29/1993 - "Two novel fluorescent glycolipids, LRO-glucosylceramide (LRO-GC) and LRO-trihexosylceramide (LRO-THC) were synthesized and utilized for estimating activities of the lysosomal, acid beta-glucosidase in cell extracts and intact skin fibroblasts, derived from normal individuals and patients with Gaucher disease subtypes. "

Related Drugs and Biologics

1.	Glycolipids
2.	Glucosylceramides (Glucocerebrosides)
3.	Glucosylceramidase (Glucocerebrosidase)
4.	Cell Extracts
5.	lissamine rhodamine sulfonylamidosphingosyl- trihexosylceramide