lysyl-gingivain

a 70-kDa thiol lysyl-proteinase that cleaves kininogens and fibrinogen; isolated from Porphyromonas gingivalis; functions also as a lysyl-amidase; preferentially cleaves the P1-Lys position of tripeptide substrates

Also Known As:

Lys-gingivain

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        lysyl-gingivain: 1
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        lysyl-gingivain: 1

Related Diseases

1.	Periodontitis 04/15/1993 - "These data suggest that lys-gingivain is a very potent proteinase that would be fully functional in anaerobic periodontal crevices and might participate in the pathogenesis of periodontitis. "

Related Drugs and Biologics

1.	Peptide Hydrolases (Proteases)