Nck protein (NCK adaptor protein 1)

a 47 kDa SH protein; an adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates; has been sequenced; homolgous Nck gene found in rat, however not classified in the RGD; NM_006153 (human), NM_010878

Also Known As:

NCK adaptor protein 1; NCK adaptor protein 1, human; NCK protein, human; NCK-alpha protein; NCK-alpha protein, human; NCK1 protein, human; NCKalpha protein, human; Nck protein, mouse; Nck-1 protein; Nck1 protein, mouse; SH2-SH3 adaptor protein NCK-alpha; mNck-alpha protein, mouse; non-catalytic region of tyrosine kinase adaptor protein 1, mouse

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - Nck protein: 3

Experts

1.	Chen, Sheng: 1 article (10/2020)
2.	Li, Linting: 1 article (10/2020)
3.	Li, Yong-Qiang: 1 article (10/2020)
4.	Nie, Yunyu: 1 article (10/2020)
5.	Qiu, Jiaming: 1 article (10/2020)
6.	Wang, Jianhao: 1 article (10/2020)
7.	Wang, Miaomiao: 1 article (10/2020)
8.	Wang, Rui: 1 article (10/2020)
9.	Xia, Jiang: 1 article (10/2020)
10.	Zhang, Yu: 1 article (10/2020)

Related Diseases

1.	Tick Bites 01/01/2020 - "In response to tick bites, the host skin promotes coagulation through high expression of fibrinogen and fibronectin, and vascular repair through high expression of integrin linked kinase and tenascin C, as well as accelerated phosphorylation of the phosphorylated protein Nck adaptor protein 1, and wound healing through high expression of ezrin and integrin. "
2.	Melanoma (Melanoma, Malignant) 01/01/1995 - "Two human genes containing NotI sites, ADP-ribosylation factor (ARF2) and melanoma NCK protein, were mapped by fluorescence in situ hybridization to 3p21.2-->p21.1 and 3q21, respectively. "
3.	Infections 10/01/2020 - "Here we report the design of a synthetic peptide that reacts precisely with a unique cysteine of the Nck-SH3.2 domain, blocks the binding site of the Nck protein, and prevents EPEC infection of Caco-2 cells. "

Related Drugs and Biologics

1.	ADP-Ribosylation Factors (ADP-Ribosylation Factor)
2.	Tenascin
3.	Integrins
4.	Proteins (Proteins, Gene)
5.	Peptides (Polypeptides)
6.	Fibronectins (Fibronectin)
7.	Fibrinogen (Factor I)
8.	Cysteine (L-Cysteine)
9.	integrin-linked kinase
10.	ezrin