2',3'-cyclic GMP

was GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93; use CYCLIC GMP to search 1980-93

Also Known As:

2',3'-cyclic GMP, lithium salt; 2',3'-cyclic GMP, monosodium salt; 2',3'-cyclic GMP, sodium salt; guanosine cyclic 2',3'-monophosphate; guanosine cyclic 2,3 monophosphate; guanosine cyclic-2',3'-monophosphate; guanosine, cyclic 2',3'-(hydrogen phosphate)

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	An, Jie: 1 article (01/2022)
2.	Cao, Shujie: 1 article (01/2022)
3.	Elkon, Keith B: 1 article (01/2022)
4.	Guan, Wenli: 1 article (01/2022)
5.	Lu, Kuan: 1 article (01/2022)
6.	Ren, Mengtian: 1 article (01/2022)
7.	Shang, Mengdi: 1 article (01/2022)
8.	Skopelja-Gardner, Sladjana: 1 article (01/2022)
9.	Zhou, Chuanzheng: 1 article (01/2022)
10.	Deschamps, Thibaut: 1 article (01/2017)

Related Diseases

1.	Bites and Stings (Sting) 11/16/2023 - "The most potent natural agonist of STING, 2',3'-cyclic GMP-AMP (2',3'-cGAMP), is subject to nuclease-mediated inherent metabolic instability, thereby placing limits on its clinical efficacy. " 01/01/2022 - "2',3'-Cyclic GMP-AMP dinucleotides (2',3'-cGAMP), the key second messengers produced by cGAS, play a pivotal role in cGAS-STING signalling by binding and activating STING. " 01/01/2022 - "2',3'-Cyclic GMP-AMP Dinucleotides for STING-Mediated Immune Modulation: Principles, Immunotherapeutic Potential, and Synthesis." 11/15/2023 - "All five analogs showed stronger STING inhibition than H-151 on the 2',3'-cyclic GMP-AMP-induced expression of interferon regulatory factors (IRFs) in a STINGR232 knock-in THP-1 reporter cell line. " 01/01/2023 - "We demonstrate through ex vivo and in vivo experiments that the pathway is inadequately activated in ΔF condition and the use of direct STING agonists, as 2',3'-cyclic GMP-AMP (2', 3' cGAMP), is able to restore the immune response against bacterial colonization. "
2.	Infections 01/01/2017 - "UL46 was also required for the inhibition of the 2',3'-cyclic GMP-AMP (cGAMP)-dependent immune responses during infection. "

Related Drugs and Biologics

1.	Adenosine Monophosphate (AMP)
2.	cyclic guanosine monophosphate-adenosine monophosphate
3.	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)
4.	Interferon Regulatory Factors
5.	Cytokines
6.	Proteins (Proteins, Gene)
7.	Prodrugs
8.	Phosphotransferases (Kinase)
9.	Ligands
10.	Interferons