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5-(4-nitrophenyl)-2-furoic acid (NPFA)

metabolite of dantrolene; structure given in first source

Also Known As:

NPFA; 5-(p-nitrophenyl)-2-furancarboxylic acid; 2-Furancarboxylic acid, 5-(4-nitrophenyl)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - 5-(4-nitrophenyl)-2-furoic acid: 1

Related Diseases

1.

Neoplasms (Cancer)

01/01/2023 - "The combination of low doses of vincristine together with intravenous administration of NPFA nanoparticles containing RCM1 effectively reduced RMS tumor volumes, increased tumor cell death and decreased tumor cell proliferation in RMS tumors compared to RCM1 or vincristine alone. "
01/01/2023 - "Since RCM1 is highly hydrophobic, we developed innovative nanoparticle delivery system containing poly-beta-amino-esters and folic acid (NPFA), which efficiently delivers RCM1 to mouse RMS tumors in vivo. "

Related Drugs and Biologics

1.	Vincristine (Oncovin)
2.	Folic Acid (Vitamin M)
3.	Esters

Related Therapies and Procedures

1.	Intravenous Administration