xanthoxyline

isolated from Sebastiania schottiana (Euphorbiaceae); structure given in first source; also present in Xanthoxylum, Rutaceae, Artemisia and other plants

Also Known As:

2-hydroxy-4,6-dimethoxyacetophenone; brevifolin; xanthoxylin; Ethanone, 1-(2-hydroxy-4,6-dimethoxyphenyl)-

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Acetophenones: 16
    - xanthoxyline: 5

Experts

1.	Bansal, Yogita: 1 article (01/2022)
2.	Kaur, Sukhvir: 1 article (01/2022)
3.	Bezerra, Daniel P: 1 article (01/2018)
4.	Carlos, Rose M: 1 article (01/2018)
5.	Dias, Rosane B: 1 article (01/2018)
6.	Dos Santos, Edjane R: 1 article (01/2018)
7.	Neves, Sara P: 1 article (01/2018)
8.	Nogueira, Paulo C L: 1 article (01/2018)
9.	Oliveira, Regina M M: 1 article (01/2018)
10.	Rocha, Clarissa A G: 1 article (01/2018)

Related Diseases

1.	Wounds and Injuries (Trauma) 09/01/2006 - "Brevifolin and 8,9-single-epoxy brevifolin show protective effective against acute and chronic liver injuries, and the mechanism is relevant to antagonizing the lipid peroxidation of free radical and improving the blood circulation."
2.	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 07/17/2023 - "Twenty-six chemical compounds were identified in CpEO, elemicin, bicyclogermacrene, caryophyllene, brevifolin, and 2,4,6-trimethoxy-styrene. "
3.	Chagas Disease (American Trypanosomiasis) 10/15/2009 - "In the search of molecules that can serve as leads in the design of a new drug for the treatment of Chagas' disease, we found that some brevifolin carboxylate derivatives isolated from Geranium bellum Rose, inactivate triosephosphate isomerase from Trypanosoma cruzi (TcTIM) in a species-specific manner. "
4.	Hepatocellular Carcinoma (Hepatoma) 01/01/2018 - "In this paper, we report the synthesis of a novel ruthenium complex with xanthoxylin (RCX) and the investigation of its cellular and molecular action in human hepatocellular carcinoma HepG2 cells. "
5.	Alzheimer Disease (Alzheimer's Disease) 01/01/2022 - "Design, molecular Docking, synthesis and evaluation of xanthoxylin hybrids as dual inhibitors of IL-6 and acetylcholinesterase for Alzheimer's disease."

Related Drugs and Biologics

1.	Free Radicals
2.	8,9-single-epoxy brevifolin
3.	Interleukin-6 (Interleukin 6)
4.	Triose-Phosphate Isomerase (Triosephosphate Isomerase)
5.	Ruthenium
6.	Acetylcholinesterase
7.	caryophyllene
8.	elemicin