HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
cortifen
Russian drug; complex ester of 11-deoxy-17-hydroxycorticosterone & chlorphenacyl
Also Known As:
corticosterone 11-deoxy-17alpha-hydroxy-21-(N-di-(2-chloroethyl)aminophenyl acetate); cortiphen; kortifen
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Pregnanes: 9
Pregnenes: 1
Pregnenediones
Corticosterone: 4354
cortifen: 5
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Adrenal Cortex Hormones: 62914
Hydroxycorticosteroids: 7
11-Hydroxycorticosteroids: 56
Corticosterone: 4354
cortifen: 5
Organic Chemicals: 133
Hydrocarbons: 1713
Halogenated Hydrocarbons: 42
Mustard Compounds: 3
Nitrogen Mustard Compounds: 2
cortifen: 5
Experts
1.
Bogdanova, L A
: 1 article (10/2016)
2.
Kaledin, V I
: 1 article (10/2016)
3.
Morozkova, T S
: 1 article (10/2016)
4.
Nikolin, V P
: 1 article (10/2016)
5.
Popova, N A
: 1 article (10/2016)
6.
Tornuev, Yu V
: 1 article (10/2016)
Related Diseases
1.
Neoplasms (Cancer)
01/01/1990 - "
The antitumour activity of cortiphen synthesized at the All-Union Cancer Research Centre of the USSR Academy of Medical Sciences was studied on human tumour strains transplanted into nude mice and rats.
"
01/01/1990 - "
[Effects of cortiphen on human tumor strains transplanted into athymic mice and rats].
"
01/01/1989 - "
Practically all the tumors were shown to respond to cortiphen action.
"
10/01/2016 - "
Liposomal and free cortifen (hydrophobic hormonal cytostatic) produced nearly the same effects on solid tumor growth.
"
01/01/1989 - "
Cortiphen was found to interact with glucocorticoid receptors in both animal and human tumors.
"
2.
Sarcoma (Soft Tissue Sarcoma)
01/01/1990 - "
Two strains of colon adenocarcinoma out of three have displayed an expressed sensitivity to cortiphen, while melanoma and Jewing sarcoma strains proved to be weakly sensitive to the preparation.
"
01/01/1990 - "
Cortiphen and cyclophosphamide were studied for their effect on the mixed uterus sarcoma induced primarily by 1,2-dimethylhydrazine and oestradiol-dipropionate in CBA mice and its transplants.
"
01/01/1990 - "
[Effects of cortiphen and cyclophosphamide in uterine sarcoma induced primarily by 1,2-dimethylhydrazine and estradiol dipropionate in CBA mice].
"
3.
Melanoma (Melanoma, Malignant)
01/01/1990 - "
Two strains of colon adenocarcinoma out of three have displayed an expressed sensitivity to cortiphen, while melanoma and Jewing sarcoma strains proved to be weakly sensitive to the preparation.
"
4.
Kidney Neoplasms (Kidney Cancer)
01/01/1990 - "
Cortiphen was found to possess an expressed activity to kidney cancer, cancer of corpus uteri, chorionepithelioma, fibrosarcoma.
"
5.
Fibrosarcoma
01/01/1990 - "
Cortiphen was found to possess an expressed activity to kidney cancer, cancer of corpus uteri, chorionepithelioma, fibrosarcoma.
"
Related Drugs and Biologics
1.
Cytostatic Agents
2.
Glucocorticoid Receptors (Glucocorticoid Receptor)
3.
1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)
4.
Estradiol (Delestrogen)
5.
Cyclophosphamide (Cytoxan)
6.
Antineoplastic Agents (Antineoplastics)
7.
estradiol dipropionate