butrin

antihepatotoxic principle from Butea monosperma (Fabaceae) flowers; structure given in first source

Also Known As:

7,3',4'-trihydroxyflavanone-7,3'-diglucoside; 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-2-(3-(beta-D-glucopyranosyloxy)-4-hydroxyphenyl)-2,3-dihydro-, (S)-

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        butrin: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        butrin: 2

Experts

1.	Mathan, Ganeshan: 2 articles (06/2017 - 10/2016)
2.	Subramaniyan, Boopathi: 2 articles (06/2017 - 10/2016)
3.	Kumar, Vijay: 1 article (06/2017)
4.	Polachi, Navaneethakrishnan: 1 article (10/2016)

Related Diseases

1.	Liver Neoplasms (Liver Cancer) 10/01/2016 - "The compound isocoreopsin showed significantly greater efficacy in cell death on human colon and liver cancer cell lines (50 μg/mL in HT-29 and 100 μg/mL in HepG2) than butrin (100 μg/mL in HT-29 and 500 μg/mL in HepG2) and isobutrin (80 μg/mL in HT-29 and 150 μg/mL in HepG2). "
2.	Colorectal Neoplasms (Colorectal Cancer) 06/01/2017 - "Effect of sodium salt of Butrin, a novel compound isolated from Butea monosperma flowers on suppressing the expression of SIRT1 and Aurora B kinase-mediated apoptosis in colorectal cancer cells."
3.	Colonic Neoplasms (Colon Cancer) 10/01/2016 - "These results suggest that isocoreopsin, butrin and isobutrin are the important key compounds for the chemoprevention of colon cancer and isocoreopsin can be considered as a promising novel drug."

Related Drugs and Biologics

1.	isobutrin
2.	isocoreopsin
3.	Aurora Kinase B
4.	Sirtuin 1
5.	Sodium
6.	Salts

Related Therapies and Procedures

1.	Chemoprevention