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ferlixit

used to induce siderosis in femal Wistar albino rats

Also Known As:

iron(III) gluconate complex; Iron, tris(D-gluconato-O1,O2)-

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Iron Compounds: 87
  - Ferric Compounds: 6
    - ferlixit: 1
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - Gluconates: 16
        ferlixit: 1
  - Acyclic Acids
    - Sugar Acids: 4
      - Gluconates: 16
        ferlixit: 1
Carbohydrates: 22023
- Sugar Acids: 4
  - Gluconates: 16
    - ferlixit: 1

Experts

1.	Battaglia, Anna Martina: 1 article (01/2022)
2.	Biamonte, Flavia: 1 article (01/2022)
3.	Costanzo, Francesco: 1 article (01/2022)
4.	Faniello, Maria Concetta: 1 article (01/2022)
5.	Levi, Sonia: 1 article (01/2022)
6.	Perrotta, Ida Daniela: 1 article (01/2022)
7.	Sacco, Alessandro: 1 article (01/2022)
8.	Scalise, Mariangela: 1 article (01/2022)
9.	Torella, Daniele: 1 article (01/2022)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 01/01/2022 - "This study proposes both the baseline and the induced intracellular free iron level as a significant determinant of ferroptosis sensitivity and discusses the potential use of ferlixit in combination with erastin to overcome ferroptosis chemoresistance in ovarian cancer." 01/01/2022 - "Erastin and/or the iron compound ferlixit were used to trigger ferroptosis in HEY, COV318, PEO4, and A2780CP ovarian cancer cell lines. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2022 - "Notably, the use of ferlixit sensitizes COV318 cells to erastin through a NCOA4-independent intracellular iron accumulation and mitochondrial dysfunction. "

Related Drugs and Biologics

1.	Iron
2.	erastin