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nargenicin A1

from Saccharopolyspora hirsuta; structure given in first source

Also Known As:

Nodusmicin, 9-(1H-pyrrole-2-carboxylate)

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - nargenicin A1: 2

Experts

1.	Han, Jang Mi: 1 article (03/2021)
2.	Jung, Hye Jin: 1 article (03/2021)
3.	Lee, Woo-Haeng: 1 article (03/2021)
4.	Oh, Tae-Jin: 1 article (03/2021)
5.	Sohng, Jae Kyung: 1 article (03/2021)
6.	Cha, Hee-Jae: 1 article (01/2019)
7.	Choi, Yung Hyun: 1 article (01/2019)
8.	Han, Min Ho: 1 article (01/2019)
9.	Hong, Sang Hoon: 1 article (01/2019)
10.	Hong, Su-Hyun: 1 article (01/2019)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2019 - "In addition, apoptosis induction by tacrolimus was accompanied by increases in ROS generation and decreases in adenosine triphosphate (ATP) levels caused by mitochondrial dysfunction, and these changes were significantly attenuated in the presence of nargenicin A1, which further indicated tacrolimus-induced apoptosis involved an oxidative stress-associated mechanism. "
2.	Stomach Neoplasms (Stomach Cancer) 03/01/2021 - "Identification of Cyclophilin A as a Potential Anticancer Target of Novel Nargenicin A1 Analog in AGS Gastric Cancer Cells."
3.	Neoplasms (Cancer) 03/01/2021 - "We recently discovered a novel nargenicin A1 analog, 23-demethyl 8,13-deoxynargenicin (compound 9), with potential anti-cancer and anti-angiogenic activities against human gastric adenocarcinoma (AGS) cells. "
4.	Adenocarcinoma 03/01/2021 - "We recently discovered a novel nargenicin A1 analog, 23-demethyl 8,13-deoxynargenicin (compound 9), with potential anti-cancer and anti-angiogenic activities against human gastric adenocarcinoma (AGS) cells. "

Related Drugs and Biologics

1.	Cyclophilin A
2.	Tacrolimus (Prograf)
3.	Adenosine Triphosphate (ATP)