oxmetidine
specific histamine H2 receptor antagonist with MW around 1.8 times that of cimetidine; differs from cimetidine by carrying an isocytosine ring instead of a cyanoguanidine in side chain; RN given refers to parent cpd
Also Known As:
SK&F 92994; SK&F-92994; SKF 92994; oxmetidine dihydrochloride
Networked: 20
relevant articles (1 outcomes,
8 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Related Diseases
1. | Duodenal Ulcer (Curling's Ulcer)
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2. | Liver Cirrhosis (Hepatic Cirrhosis)
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3. | Fistula
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4. | Ulcer
01/01/1985
- " At weeks 4 and 6, 72.5% and 85%, respectively, of ulcers were completely healed by oxmetidine, and 36.8% and 41.7%, respectively, by placebo. " 04/13/1983
- " Of the 15 patients receiving oxmetidine, 11 (73 percent) had healed their ulcers in four weeks, while 14 (93 percent) had healed their ulcers in eight weeks. " 10/01/1983
- " The ulcer healing rate after 4 weeks of treatment was 80% in the oxmetidine group and 74% in the cimetidine group and, after 8 weeks, 92% and 86%, respectively. " 10/01/1982
- " After four weeks, ulcers were healed in 74% of the cimetidine-treated patients and in 78% of the oxmetidine-treated patients (p greater than 0.05). " 12/01/1981
- " The disappearance of the ulcer crater leading to complete reepithelization of the bulbs or to the presence of erosions occurred in 17 out of 19 (89.6%) patients treated with oxmetidine, and in 13 out of 20 (65.0%) patients treated with cimetidine (n.s.). "
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5. | Peptic Ulcer (Peptic Ulcers)
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