phenylhydroxylamine
RN given refers to parent cpd
Also Known As:
hydroxylaminobenzene; phenylhydroxylamine hydrochloride
Networked: 9
relevant articles (1 outcomes,
0 trials/studies)
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Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Methemoglobinemia
09/01/1987
- " These data are consistent with phenylhydroxylamine being the sole mediator of aniline-induced methemoglobinemia in these rats." 09/01/1987
- " Compared with the in vitro data, the relative potencies of the aminophenols for methemoglobinemia in rats after intraperitoneal injections were reduced with respect to phenylhydroxylamine (to 100:4:1, respectively), apparently as a result of rapid in vivo clearance of the aminophenols. " 09/01/2007
- " Aniline-induced methemoglobinemia, loss of circulating blood cells, blood stability, glutathione depletion and membrane cytoskeletal changes were assessed following exposure to phenylhydroxylamine (PHA), para-fluoro-, para-bromo-, and para-iodo in male Sprague-Dawley rats. " 09/01/1987
- " To determine the relative contributions of these aniline metabolites to aniline-induced methemoglobinemia in rats, we determined time courses of methemoglobinemia in rat erythrocyte suspensions and in rats after treatment with 2- and 4-aminophenol, phenylhydroxylamine, and aniline. " 05/01/1975
- " It was found that by a single administration, methemoglobinemia was induced by phenylhydroxylamine (PHA), nitrobenzene (NB), aniline (A), 2-chloro-A (2-Cl-A), 3-Cl-A, 4-Cl-A, acetanilide (AA), phenacetin (PA), N-(4-chlorophenyl)ethylurethane (CPU), hydroxylamine (HA) and sodium nitrite (SN), and was not observed with phenylurethane, HPU, methylhydroxylamine (MHA), methylamine and nitromethane (NM). "
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2. | Thrombosis (Thrombus)
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3. | Photosensitivity Disorders (Photodermatitis)
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4. | Neoplasms (Cancer)
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5. | Necrosis
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