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dehydrosanol (bemetizide)
structure
Also Known As:
bemetizide
; bemetecide; bemetizid; 6-chlor-3,4-dihydro-3-(alpha-methylbenzyl)-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide
Networked:
15
relevant articles (
0
outcomes,
4
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazides: 1584
Benzothiadiazines: 3
dehydrosanol: 15
Sulfones: 534
Sulfonamides: 2809
Benzothiadiazines: 3
dehydrosanol: 15
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzothiadiazines: 3
dehydrosanol: 15
Related Diseases
1.
Hypertension (High Blood Pressure)
12/08/1978 - "
[Experiences with a combination of bemetizide and triamterene in the ambulatory treatment of hypertension.
"
01/01/1983 - "
Placebo-controlled trial of a combination of bemetizide and triamterene ('Hypertane') in mild or moderate hypertension.
"
10/22/1982 - "
[Treatment of hypertension with bupranolol, bemetizide and triamterene].
"
04/01/1982 - "
[Double-blind controlled study of the therapeutic effectiveness and tolerance of the guabenxan-bemetizid combination as compared with guanethidine-hydrochlorothiazide in arterial hypertension in the aged].
"
04/12/1985 - "
In 20 patients with essential arterial hypertension, grade II or III, the haemodynamic effect of a fixed combination of antihypertensive drugs (bemetizide, triamteren, bupranolol and dihydralazine) was studied by percutaneously-introduced flow-guided catheter in the pulmonary artery before, after three weeks and at the end of a six-month period of treatment; systemic arterial blood pressures were measured by the cuff method.
"
2.
Essential Hypertension
11/15/1989 - "
[Long-term efficacy and side effect profile of a low-dose bemetizid-triamterene combination in patients with essential hypertension].
"
01/01/1983 - "
A double-blind trial was carried out to compare the combination of 25 mg bemetizide plus 50 mg triamterene ('Hypertane') and 0.25 mg cyclopenthiazide plus 600 mg potassium chloride ('Navidrex' K) in the treatment of mild to moderate essential hypertension.
"
3.
Hypokalemia
03/01/1992 - "
During the second year of the trial, activation of the renin-angiotensin system (RAS) was significantly less pronounced as compared with the first year and the percentage of patients with hypokalemia (less than 3.5 mM) decreased from 62.5 to 25% in the bemetizide group.
"
4.
Phototoxic Dermatitis (Phototoxicity)
01/01/1997 - "
A number of sulphonamide derived oral antidiabetics (chlorpropamide, glibenclamide, glipizide, gliquidone, glymidine, tolazamide and tolbutamide) and diuretics (bemetizide, bendroflumethiazide, benzylhydrochlorothaizide, bumetanide, butizide, chlortalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide and xipamide) were investigated for phototoxicity in a cell culture model.
"
01/01/1997 - "
The oral antidiabetics chlorpropamide, glibenclamide, glipizide, gliquiudone, glymidine, tolazamide and tolbutamide, and the diuretics bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, chlortalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide, and xipamide were investigated for potential phototoxicity in vitro using a cell culture model, and in vivo in hairless mice.
"
02/01/1996 - "
A number of sulphonamide-derived oral antidiabetics (chlorpropamide, glibenclamide, glipizide, gliquidone, glymidine, tolazamide and tolbutamide) and diuretics (bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, chloratalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide and xipamide) were investigated for phototoxicity in a cell culture model.
"
03/01/1997 - "
The sulphonamide-derived oral antidiabetics chlorpropamide, glibenclamide, glipizide, gliquidone, glymidine, tolazamide and tolbutamide, and the diuretics bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, chlortalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide and xipamide were investigated for phototoxicity in a cell culture model.
"
5.
Renal Insufficiency (Renal Failure)
01/01/1994 - "
In renal failure, bemetizide increased the fractional Na+ excretion from 3% to about 10%.
"
Related Drugs and Biologics
1.
Triamterene (Dyrenium)
2.
hypertane
3.
Hydrochlorothiazide (Esidrix)
4.
Potassium Chloride
5.
Guanethidine
6.
Cyclopenthiazide
7.
guabenxan
8.
navidrex-K
9.
Xipamide
10.
Trichlormethiazide (Naqua)
Related Therapies and Procedures
1.
Catheters