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4-nitrophenyl beta-D-xyloside
Also Known As:
4-nitrophenyl beta-D-xyloside, (alpha-D)-isomer; 4-nitrophenyl-alpha-D-xylopyranoside; PNP xyloside; PNPX; p-nitrophenyl beta-D-xylopyranoside; p-nitrophenyl beta-D-xyloside; p-nitrophenylxyloside; para-nitrophenyl beta-D-xyloside
Networked:
5
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycosides: 2119
4-nitrophenyl beta-D-xyloside: 5
Related Diseases
1.
Wounds and Injuries (Trauma)
06/01/1996 - "
After inhibiting CSPG synthesis with p-nitrophenyl beta-d xylopyranoside (beta-d xyloside), wound microvascular endothelial cells were capable of attaching and spreading on the surface of a fibrin gel; however, their ability to invade the fibrin matrix was virtually eliminated.
"
2.
Melanoma (Melanoma, Malignant)
01/01/1992 - "
By blocking mouse melanoma cell production of CSPG with p-nitrophenyl beta-D-xylopyranoside (beta-D-xyloside), a compound that uncouples chondroitin sulfate from CSPG core protein synthesis, we observed a corresponding decrease in melanoma cell motility on type I collagen and invasive behavior into type I collagen gels.
"
3.
Emphysema
01/01/1997 - "
The possible involvement of proteoglycans in the pathogenesis of emphysema was studied in rats by a single intratracheal instillation of p-nitrophenyl-beta-D-xylopyranoside (beta-D-xyloside), an inhibitor of proteoglycan synthesis.
"
4.
Edema (Dropsy)
02/01/1981 - "
The effect of p-nitrophenyl beta-D-xyloside, an inhibitor of proteoglycan biosynthesis, on the growth of chick embryos was studied by injection of the single dose of 1.0 mg/egg into fertile eggs on day 3. Embryos examined on day 10 had systemic edema, and were increased not only in wet weight (142% of the non-treated embryos) but also in dry weight (125%).
"
5.
Chondrosarcoma
02/15/1982 - "
Chondroitin sulphate synthesis on proteoglycans was decreased in rat chondrosarcoma cell cultures in the presence of cycloheximide (0.1-1.0 muM) or p-nitrophenyl beta-D-xyloside (50 microM).
"
Related Drugs and Biologics
1.
xylosides
2.
Fibrin
3.
Proteoglycans (Proteoglycan)
4.
Collagen Type I (Type I Collagen)
5.
Proteins (Proteins, Gene)
6.
Gels
7.
Cycloheximide (Cicloheximide)
8.
Chondroitin Sulfates (Chondroitin Sulfate)
9.
Chondroitin