EZM2302

CARM1 inhibitor

Also Known As:

EZM-2302; GSK3359088; methyl 2-(2-(2-chloro-5-((2R)-2-hydroxy-3-(methylamino)propoxy)phenyl)-6-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methylpyrimidin-4-yl)-2,7-diazaspiro(3.5)nonane-7-carboxylate

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - EZM2302: 1
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - EZM2302: 1

Experts

1.	Allain, Christina: 1 article (12/2017)
2.	Boriack-Sjodin, Ann P: 1 article (12/2017)
3.	Chesworth, Richard: 1 article (12/2017)
4.	Copeland, Robert A: 1 article (12/2017)
5.	Drew, Allison E: 1 article (12/2017)
6.	Duncan, Kenneth W: 1 article (12/2017)
7.	Handler, Jessica L: 1 article (12/2017)
8.	Jacques, Suzanne L: 1 article (12/2017)
9.	Jin, Lei: 1 article (12/2017)
10.	Kruger, Ryan G: 1 article (12/2017)

Related Diseases

1.	Neoplasms (Cancer) 12/21/2017 - "EZM2302 is a validated chemical probe suitable for further understanding the biological role CARM1 plays in cancer and other diseases." 12/21/2017 - "Oral dosing of EZM2302 demonstrates dose-dependent in vivo CARM1 inhibition and anti-tumor activity in an MM xenograft model. "

Related Drugs and Biologics

1.	coactivator-associated arginine methyltransferase 1