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phenylmethyl N- ((1S)- 1- ((((1S)- 1- formyl- 2- (2- oxo- 3- pyrrolidinyl)ethyl)amino)carbonyl)- 3- methylbutyl)carbamate

Also Known As:

GC-373; GC373

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - phenylmethyl N-((1S)-1-((((1S)-1-formyl-2-(2-oxo-3-pyrrolidinyl)ethyl)amino)carbonyl)-3-methylbutyl)carbamate: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Lactams: 2198
    - phenylmethyl N-((1S)-1-((((1S)-1-formyl-2-(2-oxo-3-pyrrolidinyl)ethyl)amino)carbonyl)-3-methylbutyl)carbamate: 2
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Branched-Chain Amino Acids: 2289
    - Leucine: 6718
      - phenylmethyl N-((1S)-1-((((1S)-1-formyl-2-(2-oxo-3-pyrrolidinyl)ethyl)amino)carbonyl)-3-methylbutyl)carbamate: 2
  - Essential Amino Acids: 1152
    - Leucine: 6718
      - phenylmethyl N-((1S)-1-((((1S)-1-formyl-2-(2-oxo-3-pyrrolidinyl)ethyl)amino)carbonyl)-3-methylbutyl)carbamate: 2

Experts

1.	Dhama, Kuldeep: 1 article (01/2021)
2.	Sharun, Khan: 1 article (01/2021)
3.	Tiwari, Ruchi: 1 article (01/2021)

Related Diseases

1.	COVID-19 01/01/2021 - "Since both GC373 and GC376 have already been successfully used in treating animal coronavirus infection, they can be considered as strong drug candidates for COVID-19 in humans. " 11/01/2023 - "Nirmatrelvir and GC373 inhibit the SARS-CoV-2 3CL protease and hinder viral replication in COVID-19. "
2.	Coronavirus Infections 01/01/2021 - "Since both GC373 and GC376 have already been successfully used in treating animal coronavirus infection, they can be considered as strong drug candidates for COVID-19 in humans. "

Related Drugs and Biologics

1.	Peptide Hydrolases (Proteases)
2.	nirmatrelvir
3.	GC376