gomisin M2

lignan extract from fruit Schisandra chinensis (Turcz). Baill. (Schisandraceae; S. Chinensis) has antiallergic effects: inhibit mast cell activation and human immunodeficiency virus present study shows it has anti-inflammatory effects

Networked: 6 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kang, Jinjoo: 3 articles (12/2021 - 01/2019)
2.	Kim, Sang-Hyun: 3 articles (12/2021 - 01/2019)
3.	Lee, Soyoung: 3 articles (12/2021 - 01/2019)
4.	Kim, Namkyung: 2 articles (12/2021 - 07/2021)
5.	Dhakal, Hima: 2 articles (07/2021 - 01/2019)
6.	Jeong, Gil-Saeng: 2 articles (07/2021 - 01/2019)
7.	Kim, Eun-Nam: 2 articles (07/2021 - 01/2019)
8.	Chen, Yi-Li: 1 article (04/2022)
9.	Chu, Wang: 1 article (04/2022)
10.	Liang, Dong-E: 1 article (04/2022)

Related Diseases

1.	Neoplasms (Cancer) 10/14/2019 - "However, only a few investigations have been conducted on the effects of Gomisin M2 on breast cancer stem cells (CSCs), which have the ability to self-renew and differentiate, as a possible strategy to resolve cancer cell resistance to apoptosis and to improve treatments. " 04/01/2022 - "Cytotoxicity and MDR reversal effect of these compounds were screened on multidrug resistance cancer cell line MCF-7/ADR, and results showed gomisin M2 (7) could promote the efficacy of adriamycin against MCF-7/ADR."
2.	Atopic Dermatitis (Atopic Eczema) 07/21/2021 - "Gomisin M2 Ameliorates Atopic Dermatitis-like Skin Lesions via Inhibition of STAT1 and NF-κB Activation in 2,4-Dinitrochlorobenzene/Dermatophagoides farinae Extract-Induced BALB/c Mice."
3.	Inflammation (Inflammations) 12/01/2021 - "Gomisin M2 alleviates psoriasis‑like skin inflammation by inhibiting inflammatory signaling pathways." 01/01/2019 - "Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels."
4.	Breast Neoplasms (Breast Cancer) 07/14/2023 - "Correction for: Gomisin M2 from Baizuan suppresses breast cancer stem cell proliferation in a zebrafish xenograft model." 10/14/2019 - "The ability of Gomisin M2 to kill breast cancer stem cells was evaluated in vitro and in vivo. " 10/14/2019 - "It is essential to investigate the effects of Gomisin M2 on breast cancer stem cells (BCSCs). " 10/14/2019 - "Gomisin M2 from Baizuan suppresses breast cancer stem cell proliferation in a zebrafish xenograft model." 10/14/2019 - "However, only a few investigations have been conducted on the effects of Gomisin M2 on breast cancer stem cells (CSCs), which have the ability to self-renew and differentiate, as a possible strategy to resolve cancer cell resistance to apoptosis and to improve treatments. "
5.	Triple Negative Breast Neoplasms 10/14/2019 - "Gomisin M2 significantly inhibited the proliferation of the triple-negative breast cancer cell lines and mammosphere formation in breast CSCs and downregulated the Wnt/β-catenin self-renewal pathway. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Dinitrochlorobenzene (DNCB)
3.	Catenins
4.	Calcium