hypoglycemic encephalopathy

05/01/2023 - "Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation."
12/10/2018 - "Taken together, this study demonstrates that Gas attenuates the diabetic encephalopathy by inhibiting ER stress and NLRP3 inflammasome activation."
02/27/2018 - "Inhibiting the NLRP3 Inflammasome Activation with MCC950 Ameliorates Diabetic Encephalopathy in db/db Mice."
02/06/2018 - "Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation."

04/25/2013 - "Luteolin also improved the learning and memory abilities of rats with diabetic encephalopathy in a water maze test. "
05/01/2013 - "In conclusion, the present study suggested that oral supplementation of luteolin might be a potential therapeutic strategy for the treatment and/or prevention of diabetic encephalopathy."
04/25/2013 - "Luteolin attenuates neuronal apoptosis in the hippocampi of diabetic encephalopathy rats."
04/25/2013 - "These experimental findings indicate that luteolin can inhibit apoptosis of hippocampal nerve cells in rats with diabetic encephalopathy, and that this effect is mediated by an indirect antioxidative effect, the inhibition of activation of apoptosis-related factors and the activation of phosphatidylinositol 3-kinase/Akt signal pathway. "
04/25/2013 - "This study aimed to investigate the effects of luteolin on hyperglycemia-mediated apoptosis in the hippocampi of rats with streptozotocin-induced diabetic encephalopathy after injection into the tail veins, and the molecular mechanisms involved. "

01/11/2010 - "Oral supplementation of catalpol ameliorates diabetic encephalopathy in rats."
01/11/2010 - "The study suggested that oral supplementation of catalpol might be a potential therapeutic strategy for the treatment and/or prevention of diabetic encephalopathy."
01/11/2010 - "Therefore, the study was designed to investigate the effects of catalpol on diabetic encephalopathy in rats. "
11/23/2020 - "Design, microwave synthesis, and molecular docking studies of catalpol crotonates as potential neuroprotective agent of diabetic encephalopathy."
01/11/2010 - "Catalpol, an iridoid glycoside, has properties of anti-inflammation, antioxidant and decreasing blood glucose level and thus has the possibility of treating diabetic encephalopathy. "

01/01/2015 - "Those results indicate that insulin exerts direct anabolic actions in neuron-like cells by activation of its cognate receptor and prove that IGF-1R plays an important role in the pathogenesis of diabetic encephalopathy. "
01/01/2015 - "Defective cognitive function is common in patients with diabetes, suggesting that insulin normally exerts anabolic actions in neuron, namely, diabetic encephalopathy. "
03/10/2005 - "The role of impaired insulin/IGF action in primary diabetic encephalopathy."
01/01/1983 - "Enhanced hypothalamic responsiveness was considered due to improvement of diabetic encephalopathy rather than to direct CNS stimulation by insulin because the injected insulin had mostly dissipated by the time pressor responses were recorded. "
04/08/1967 - "[Post-hypoglycemic encephalopathy in diabetes treated by insulin]."

10/15/2023 - "Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling."
11/01/2016 - "In conclusion, the present study suggested that oral supplementation of resveratrol might be a potential therapeutic strategy for the treatment and/or prevention of diabetic encephalopathy."

01/01/2017 - "In the present study, neuroblastoma (SH-SY5Y) cells were used to investigate the mechanisms mediating the potential protective effects of pterostilbene (PTE) against mitochondrial metabolic impairment and oxidative stress induced by hyperglycemia for mimicking the diabetic encephalopathy. "

01/01/2020 - "However, the effect and related mechanism of quercetin on diabetic encephalopathy (DE) are still ambiguous. "
11/01/2018 - "These results indicate that quercetin exerts beneficial effects by decreasing protein glycation, oxidative stress, and inflammation through the upregulation of Glo-1, which may ameliorate diabetic encephalopathy."
01/01/2020 - "Quercetin ameliorates diabetic encephalopathy through SIRT1/ER stress pathway in db/db mice."
01/01/2020 - "In conclusion, current experimental results indicated that SIRT1/ER stress is a promising mechanism involved in quercetin-treated diabetic encephalopathy."
01/01/2020 - "Quercetin protects against diabetic encephalopathy via SIRT1/NLRP3 pathway in db/db mice."

01/01/2018 - "Morris water maze test, in vivo neuronal tracing, immunohistochemistry, and western blot analysis were performed to evaluate the protective effects of berberine in T2D-induced diabetic encephalopathy rats. "
06/01/2018 - "Berberine (BBR) has been reported to ameliorate diabetes and diabetic encephalopathy (DE). "
01/01/2018 - "Berberine Alleviates Tau Hyperphosphorylation and Axonopathy-Associated with Diabetic Encephalopathy via Restoring PI3K/Akt/GSK3β Pathway."
01/01/2021 - "Berberine elevates mitochondrial membrane potential and decreases reactive oxygen species by inhibiting the Rho/ROCK pathway in rats with diabetic encephalopathy."
06/01/2018 - "Berberine Improves Diabetic Encephalopathy Through the SIRT1/ER Stress Pathway in db/db Mice."

01/01/2020 - "Quercetin ameliorates diabetic encephalopathy through SIRT1/ER stress pathway in db/db mice."
01/01/2020 - "In conclusion, current experimental results indicated that SIRT1/ER stress is a promising mechanism involved in quercetin-treated diabetic encephalopathy."
01/01/2020 - "Quercetin protects against diabetic encephalopathy via SIRT1/NLRP3 pathway in db/db mice."
06/01/2018 - "Berberine Improves Diabetic Encephalopathy Through the SIRT1/ER Stress Pathway in db/db Mice."

01/01/2015 - "Down-regulation of CaSR expression was accompanied by neuronal injury, calcium disturbance, increased ROS production and decreased release of NO. Up-regulation of CaSR expression attenuated these changes through a positive compensatory protective mechanism to inhibit and delay diabetic encephalopathy in rats."
01/01/2015 - "Diabetic encephalopathy is a common complication of diabetes, and it may be involved in altering intracellular calcium concentrations ([Ca(2+)]i) at its onset. "
02/01/2012 - "Serum calcium concentration affects signal changes on diffusion-weighted imaging in hypoglycemic encephalopathy."
02/01/2015 - "The data suggests that L-type calcium channel blocker is beneficial in preventing cognitive deficits associated with diabetic encephalopathy through modulation of dysregulated calcium homeostasis."
02/01/2015 - "L-type calcium channel blocker ameliorates diabetic encephalopathy by modulating dysregulated calcium homeostasis."

01/01/2011 - "The results from the study provide evidence for the role of mitochondrial oxidative stress and dysfunctions in the development of diabetic encephalopathy and point towards the clinical potential of NAC as an adjuvant therapy to conventional anti-hyperglycemic regimens for the prevention and/or delaying the progression of CNS complications."
01/01/2018 - "Our findings provide a promising future of Spd-based preventions and therapies for diabetic encephalopathy."
01/01/2015 - "Therefore, L-NBP can improve the cognitive function by up-regulating the expression of NR2B in STZ-diabetic rats, which may provide the direction for future diabetic encephalopathy therapy."
12/01/2008 - "Our results emphasize the involvement of increased oxidative stress in cognitive impairment in diabetic animals and point towards the potential beneficial role of NAC as an adjuvant therapy to conventional anti-hyperglycemic regimens for the prevention and treatment of diabetic encephalopathy."
08/01/1977 - "Three patients experienced severe hypoglycemic encephalopathy during oral therapy of adult-onset diabetes mellitus. "

12/01/2014 - "Brain injury was revealed by MRI after resuscitation, with hypoxic-ischemic and hypoglycemic encephalopathy. "

04/24/2021 - "(Ginkgoaceae), a traditional Chinese medicine known to treating stroke, has a protective effect on the central nervous system and significantly improves the cognitive dysfunction caused by disease, including alzheimer disease (AD), vascular dementia, and diabetic encephalopathy. "

03/01/2003 - "One further patient was found unresponsive on the morning following discharge and was subsequently admitted to a long-term care facility with hypoglycemic encephalopathy. "

01/01/2021 - "A mouse model of diabetic encephalopathy was established by intraperitoneal injection of 1%STZ. "