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CGP55845

Also Known As:

(2S)-3-(((1S)-1-(3,4-dichlorophenyl)ethyl)amino)-2-hydroxypropyl)-(phenylmethyl)phosphinic acid

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - CGP55845: 3

Experts

1.	Iwai, Takashi: 1 article (01/2022)
2.	Oyama, Misa: 1 article (01/2022)
3.	Tanabe, Mitsuo: 1 article (01/2022)
4.	Watanabe, Shun: 1 article (01/2022)
5.	Li, Jingxin: 1 article (06/2014)
6.	Li, Xiaowei: 1 article (06/2014)
7.	Ning, Nannan: 1 article (06/2014)
8.	Wei, Chuanfei: 1 article (06/2014)
9.	Yao, Ziming: 1 article (06/2014)
10.	Zhang, Depu: 1 article (06/2014)

Related Diseases

1.	Ganglion Cysts (Ganglion) 01/01/2001 - "This indicates that ATPA stimulated an endogenous inhibitory feedback pathway that suppressed bipolar cell output.CGP55845 and CGP35348 reduced the ATPA-induced suppression of L-EPSCs in ganglion cells, signifying that part of the feedback pathway is mediated by metabotropic GABA receptors.(1,2,5,6-Tetrahydropyridine-4-yl)-methylphosphinic acid (TPMPA) and picrotoxin, GABAC receptor antagonists, reduced the ATPA effect. "
2.	Neoplasm Metastasis (Metastasis) 06/28/2014 - "Baclofen, a GABABR agonist, significantly promoted 4T1 cells invasion and migration in vitro and metastasis in vivo, an event that was attenuated by GABABR antagonist CGP55845. "
3.	Hypersensitivity (Allergy) 01/01/2022 - "Consistently, the analgesic effect of intrathecally injected NNC-711 and SNAP-5114 in mice developing mechanical hypersensitivity after partial sciatic nerve ligation was abolished by CGP55845. "

Related Drugs and Biologics

1.	GABA Receptors (GABA Receptor)
2.	Pyrrolidines
3.	Picrotoxin
4.	Baclofen
5.	Analgesics (Analgesic Drugs)
6.	methylphosphinic acid
7.	1- (2- (tris(4- methoxyphenyl)methoxy)ethyl)- 3- piperidinecarboxylic acid
8.	NNC 711 (NO 711)

Related Therapies and Procedures

1.	Ligation