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MK-1654

Respiratory Syncytial Virus Neutralizing Monoclonal Antibody

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Neutralizing Antibodies: 9981
        MK-1654: 3
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Neutralizing Antibodies: 9981
        MK-1654: 3
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Neutralizing Antibodies: 9981
        MK-1654: 3

Experts

1.	Vora, Kalpit A: 2 articles (11/2021 - 12/2019)
2.	Aliprantis, Antonios O: 1 article (11/2021)
3.	Bellanti, Francesco: 1 article (11/2021)
4.	Caro, Luzelena: 1 article (11/2021)
5.	Catchpole, Andrew P: 1 article (11/2021)
6.	Chen, Jingxian: 1 article (11/2021)
7.	Cheung, S Y Amy: 1 article (11/2021)
8.	Espeseth, Amy S: 1 article (11/2021)
9.	Fok-Seang, Juin: 1 article (11/2021)
10.	Gao, Wei: 1 article (11/2021)

Related Diseases

1.	Infections 08/01/2023 - "Background: MK-1654 is a fully human monoclonal antibody with YTE mutations currently in phase III clinical trials for prophylactic use in protecting infants from human respiratory syncytial virus infection. " 11/01/2021 - "Additionally, SNA elicited by increasing doses of MK-1654 in humans reduced RSV symptomatic infection rates with a quantitative relationship that approximated the MBMA. "
2.	Respiratory Syncytial Virus Infections 12/01/2019 - "RB1 is the parental antibody to MK-1654 which is currently in clinical development for the prevention of RSV infection in infants." 11/01/2021 - "MK-1654 is a respiratory syncytial virus (RSV) F glycoprotein neutralizing monoclonal antibody (mAb) under development to prevent RSV infection in infants. "

Related Drugs and Biologics

1.	Glycoproteins (Glycoprotein)
2.	Monoclonal Antibodies