Air crescent sign

Imaging sign of crescent shape seen in an area of pulmonary infiltrate. It is suggestive of a cavitation developed during recovery phase in lung infections, e.g., INVASIVE PULMONARY ASPERGILLOSIS.

Also Known As:

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Invasive Pulmonary Aspergillosis
2.	Aspergillosis

Experts

1.	Ide, Shuichiro: 1 article (01/2022)
2.	Ishihara, Hiroshi: 1 article (01/2022)
3.	Masuda, Kazuki: 1 article (01/2022)
4.	Saiki, Masafumi: 1 article (01/2022)
5.	Shimamura, So: 1 article (01/2022)
6.	Sogami, Yusuke: 1 article (01/2022)
7.	Uchida, Yoshinori: 1 article (01/2022)
8.	Battista, Giuseppe: 1 article (01/2021)
9.	Cavo, Michele: 1 article (01/2021)
10.	Lewis, Russell: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Air crescent sign:

1.	Sodium Glutamate (Accent)IBA 01/01/2021 - "A positive VOS was associated with the highest estimated positive likelihood ratio for EORTC/MSG-defined proven, probable, or possible IMD at baseline (20.6; 95% CI 1.4-311.2) and at day 7 follow-up (19.0; 95% CI 0.93-300.8) followed by the baseline non-contrast enhanced hypodense sign (18.3; 0.93-361.7), reverse halo (11.0; 0.47-256.5), halo sign (8.68;3.13-24.01) and air-crescent sign at day 7 (16.7; 0.93-301.0). " 10/01/2012 - "The latter differed from the former by the inclusion of patients with pulmonary infiltrates not fulfilling the three EORTC-MSG IPA specific findings of dense, well-circumscribed lesions with or without halo sign, air crescent sign or cavity. "
2.	Indicators and Reagents (Reagents)IBA 01/01/1994 - "The development of the air crescent sign on chest radiograph is an important clinical indicator of potentially fatal haemoptysis and should lead to appropriate antifungal and surgical therapy."
3.	AntigensIBA 01/01/2022 - "Based on the air-crescent sign observed on chest computed tomography and a diffuse pseudomembranous lesion on the airway epithelium that was observed via bronchoscopy along with positive serum Aspergillus antigen, a clinical diagnosis of invasive pulmonary aspergillosis (IPA) was made and liposomal amphotericin B was initiated. "
4.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/1998 - "The diagnosis was based on clinical features, failure to respond to antibiotic therapy, an air crescent sign suggestive of aspergillosis on the computed tomographic scan (39%), and retrieval of fungi by bronchoalveolar lavage (44%). "
5.	liposomal amphotericin BFDA Link 01/01/2022 - "Based on the air-crescent sign observed on chest computed tomography and a diffuse pseudomembranous lesion on the airway epithelium that was observed via bronchoscopy along with positive serum Aspergillus antigen, a clinical diagnosis of invasive pulmonary aspergillosis (IPA) was made and liposomal amphotericin B was initiated. "

Therapies and Procedures

1.	Therapeutics 12/01/1985 - "The diagnostic utility of the air crescent sign was relatively minor; cavities developed after the diagnosis was established in 50% of cases and after therapy was started in 75% of cases. " 01/01/1994 - "The development of the air crescent sign on chest radiograph is an important clinical indicator of potentially fatal haemoptysis and should lead to appropriate antifungal and surgical therapy." 01/01/1998 - "The diagnosis was based on clinical features, failure to respond to antibiotic therapy, an air crescent sign suggestive of aspergillosis on the computed tomographic scan (39%), and retrieval of fungi by bronchoalveolar lavage (44%). "
2.	X-Ray Film 04/01/1991 - "Of the latter, 6 cases had an air-crescent sign on chest X-ray films and 8 cases were culture-positive. "