JWX-A0108

Also Known As:

6-(2-chloro-6-methylphenyl)-2-((3-fluoro-4-methylphenyl)amino)thiazolo(4,5-d)pyrimidin-7(6H)-one

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

1.	Schizophrenia (Dementia Praecox) 06/01/2019 - "Our results demonstrate that JWX-A0108 is a novel type I PAM of α7 nAChR, which may be beneficial for improvement of cognitive deficits commonly found in neuropsychiatric disorders such as schizophrenia and Alzheimer's disease."
2.	Alzheimer Disease (Alzheimer's Disease) 06/01/2019 - "Our results demonstrate that JWX-A0108 is a novel type I PAM of α7 nAChR, which may be beneficial for improvement of cognitive deficits commonly found in neuropsychiatric disorders such as schizophrenia and Alzheimer's disease."
3.	Inflammation (Inflammations) 07/01/2021 - "JWX-A0108, a positive allosteric modulator of α7 nAChR, attenuates cognitive deficits in APP/PS1 mice by suppressing NF-κB-mediated inflammation."