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sisunatovir

Also Known As:

1'-((5-(aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-1,3-benzodiazol-2-yl)methyl)-6'-fluoro-1',2'-dihydrospiro(cyclopropane-1,3'-indole)-2'-one; RV521

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - sisunatovir: 2

Experts

1.	Harland, Rachel: 2 articles (01/2021 - 01/2020)
2.	Littler, Edward: 2 articles (01/2021 - 01/2020)
3.	Mathews, Neil: 2 articles (01/2021 - 01/2020)
4.	Powell, Kenneth: 2 articles (01/2021 - 01/2020)
5.	Tait, Dereck: 2 articles (01/2021 - 01/2020)
6.	Thomas, Elaine: 2 articles (01/2021 - 01/2020)
7.	Angell, Richard M: 1 article (01/2021)
8.	Bedernjak, Alexandre: 1 article (01/2021)
9.	Chuckowree, Irina: 1 article (01/2021)
10.	Cockerill, G Stuart: 1 article (01/2021)

Related Diseases

1.	Respiratory Syncytial Virus Infections 01/01/2021 - "RV521 exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. "
2.	Infections 01/01/2020 - "After infection was confirmed (or 5 days after challenge virus inoculation), subjects received RV521 (350 mg or 200 mg) or placebo orally every 12 h for 5 days. "

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)