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DMC-BH
Demethoxycurcumin analog
Networked:
3
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Diarylheptanoids: 471
DMC-BH: 3
Acyclic Hydrocarbons
Alkanes: 241
Heptanes: 70
Diarylheptanoids: 471
DMC-BH: 3
Experts
1.
Shi, Lei
: 2 articles (11/2020 - 01/2020)
2.
Sun, Guan
: 2 articles (11/2020 - 01/2020)
3.
Zhang, Yong
: 1 article (11/2020)
4.
Zhu, Haifeng
: 1 article (01/2020)
Related Diseases
1.
Neoplasms (Cancer)
11/18/2020 - "
These results suggest that the DMC analogue DMC-BH has potent anti-tumor properties that warrant further study.
"
11/18/2020 - "
DMC-BH exhibited potent anti-tumor activity in both the ectopic xenograft and PDTX models.
"
01/01/2020 - "
In addition, our results show that DMC-BH effectively crosses the blood-brain barrier to inhibit the growth of intracranial GSC tumors in vivo.
"
11/18/2020 - "
Indeed, bioluminescence measurements showed that DMC-BH exerted a significantly greater anti-tumor effect on orthotopic glioma growth than DMC.
"
11/18/2020 - "
We evaluated the anti-tumor effects of DMC-BH in an ectopic xenograft model, an orthotopic glioblastoma xenograft model and a patient-derived tumor xenograft (PDTX) model.
"
2.
Glioma (Gliomas)
11/18/2020 - "
Western blotting showed that DMC-BH significantly decreased p-Akt and p-mTOR expression in orthotopic glioma tissues.
"
11/18/2020 - "
DMC-BH was cytotoxic against various glioma cells including SHG-44, C6, U251, U87, A172 and primary glioma cells.
"
11/18/2020 - "
Indeed, bioluminescence measurements showed that DMC-BH exerted a significantly greater anti-tumor effect on orthotopic glioma growth than DMC.
"
01/01/2023 - "
DMC-BH, a curcumin analog, has been reported to possess anticancer properties against human gliomas.
"
01/01/2020 - "
Demethoxycurcumin analogue DMC-BH inhibits orthotopic growth of glioma stem cells by targeting JNK/ERK signaling.
"
3.
Colorectal Neoplasms (Colorectal Cancer)
01/01/2023 - "
Promising antitumor effects of the curcumin analog DMC-BH on colorectal cancer cells.
"
4.
Glioblastoma (Glioblastoma Multiforme)
11/18/2020 - "
We evaluated the anti-tumor effects of DMC-BH in an ectopic xenograft model, an orthotopic glioblastoma xenograft model and a patient-derived tumor xenograft (PDTX) model.
"
11/18/2020 - "
Demethoxycurcumin analogue DMC-BH exhibits potent anticancer effects on orthotopic glioblastomas.
"
Related Drugs and Biologics
1.
demethoxycurcumin
2.
Curcumin