bitter melon extract

01/01/2018 - "In recent times, bitter melon extract (BME) has gained significant attention for its anticancer efficacy against various malignancies. "
05/31/2016 - "Together, our findings offer a new insight into how bitter melon extract inhibits head and neck tumor growth by modulating cell proliferation and Treg populations, with implications for how to control tumor-infiltrating lymphocytes and tumor progression. "
11/01/2018 - "We have recently shown that bitter melon extract (BME) treatment was more effective in inhibition of TNBC tumor growth in mouse models as compared to ER positive breast tumor growth. "
01/01/2018 - "We have previously observed that bitter melon (Momordica charantia) extract (BME) exerts antiproliferative activity against several cancers including HNSCC. "
01/01/2013 - "We hypothesized that treatment of HNSCC cells with a dietary product such as bitter melon extract (BME) modulates multiple signaling pathways and regresses HNSCC tumor growth in a preclinical model. "

09/12/2017 - "We have previously shown the anti-proliferative activity of bitter melon extract (BME) in breast cancer cells. "
09/12/2017 - "Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death."
03/01/2010 - "Bitter melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis."
11/01/2018 - "We have recently shown that bitter melon extract (BME) treatment was more effective in inhibition of TNBC tumor growth in mouse models as compared to ER positive breast tumor growth. "
03/01/2010 - "In this study, we have used human breast cancer cells, MCF-7 and MDA-MB-231, and primary human mammary epithelial cells as an in vitro model to assess the efficacy of bitter melon (Momordica charantia) extract (BME) as an anticancer agent. "

01/01/2018 - "Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats."
01/01/2017 - "When applied locally to diabetic wounds, bitter melon extract prevents regression of granulation tissue and blood vessels, thus accelerating and improving wound healing."
01/01/2017 - "Bitter Melon Extract Promotes Granulation Tissue Growth and Angiogenesis in the Diabetic Wound."
04/07/2021 - "Co-electrospun nanofibrous mats loaded with bitter gourd (Momordica charantia) extract as the wound dressing materials: in vitro and in vivo study."
01/01/2018 - "The aim of this study was to investigate the efficacy of dressings using topically administered bitter melon extract with olive oil, pure olive oil, nitrofurazone, and saline in the healing of ischemic wounds. "

04/01/2023 - "This study was performed to investigate the effects of bitter melon extract (BME) on glucose metabolism, insulin resistance, and various metabolic parameters of participants with prediabetes. "
05/04/2009 - "Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats."
02/17/2021 - "Metabolite Profile of Cucurbitane-Type Triterpenoids of Bitter Melon (Fruit of Momordica charantia) and Their Inhibitory Activity against Protein Tyrosine Phosphatases Relevant to Insulin Resistance."
01/01/2020 - "Promising results are obtained by treatment with Metformin, or possibly Momordica charantia extract, which will correct insulin resistance, with Meldonium improving the transportation of glucose into the mitochondria, with sodium dichloroacetate activating pyruvate dehydrogenase, and with nutraceutical support reducing oxidative and inflammatory impairment."

01/01/2017 - "This study shows that Momordica charantia fruit juice, by lowering the hyperglycemia, induced a shift of proinflammatory Th1 phenotype in T1D rats towards a favorable anti-inflammatory Th2 status. "
06/01/2020 - "Taken together, these results indicate that administration of an EtOAc-soluble fraction improved hyperglycemia and hepatic steatosis, suggesting that this fraction may be responsible for both the antidiabetic and anti-inflammatory effects of bitter melon fruit."