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isomyosmine

synthetic derivative of tobacco alkaloids

Also Known As:

3-(3,4-Dihydro-2H-pyrrol-2-yl)pyridine; MYMD-1

Networked: 3 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - isomyosmine: 3

Experts

1.	Caturegli, Patrizio: 2 articles (01/2020 - 01/2019)
2.	Glenn, Justin D: 1 article (01/2020)
3.	Pantoja, Itzy Morales: 1 article (01/2020)
4.	Whartenby, Katharine A: 1 article (01/2020)
5.	Chalan, Paulina: 1 article (01/2019)
6.	Di Dalmazi, Giulia: 1 article (01/2019)

Related Diseases

1.	Thyroiditis 01/01/2019 - "Overall, the study suggests that MYMD-1 ameliorates thyroiditis acting on specific lymphoid subsets. " 01/01/2019 - "MYMD-1 decreased the incidence and severity (p < 0.001) of thyroiditis, as assessed by histopathology. " 01/01/2019 - "To assess the effect and mechanism(s) of the action of MYMD-1, we chose the NOD.H-2h4 mouse model of spontaneous thyroiditis. "
2.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/01/2020 - "MYMD-1, a novel alkaloid compound, ameliorates the course of experimental autoimmune encephalomyelitis." 01/01/2020 - "The goal of the present study was to determine whether MYMD-1 would produce similar beneficial effects in a mouse model of MS, experimental autoimmune encephalomyelitis (EAE) induced by immunization with myelin oligodendrocyte glycoprotein. "
3.	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 01/01/2019 - "MYMD-1, a Novel Immunometabolic Regulator, Ameliorates Autoimmune Thyroiditis via Suppression of Th1 Responses and TNF-α Release." 01/01/2020 - "MYMD-1 is a synthetic plant alkaloid that has been shown to ameliorate the course of autoimmune thyroiditis. "
4.	Body Weight (Weight, Body) 01/01/2023 - "MyMD-1 also improved several health span characteristics, resulting in milder body weight loss, greater muscle strength, and slower progression to frailty. "
5.	Frailty 01/01/2023 - "MyMD-1 also improved several health span characteristics, resulting in milder body weight loss, greater muscle strength, and slower progression to frailty. "

Related Drugs and Biologics

1.	Alkaloids
2.	Myelin-Oligodendrocyte Glycoprotein